ID   ACR30_BPD31             Reviewed;          90 AA.
AC   Q6TM72;
DT   24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Anti-CRISPR protein 30 {ECO:0000303|PubMed:23242138};
DE   AltName: Full=Gene product 30 {ECO:0000305};
DE            Short=gp30;
GN   Name=orf30 {ECO:0000312|EMBL:AAQ94468.1};
OS   Pseudomonas phage D3112 (Bacteriophage D3112).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Casadabanvirus.
OX   NCBI_TaxID=10708 {ECO:0000312|Proteomes:UP000000875};
OH   NCBI_TaxID=287; Pseudomonas aeruginosa.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=14702309; DOI=10.1128/jb.186.2.400-410.2004;
RA   Wang P.W., Chu L., Guttman D.S.;
RT   "Complete sequence and evolutionary genomic analysis of the Pseudomonas
RT   aeruginosa transposable bacteriophage D3112.";
RL   J. Bacteriol. 186:400-410(2004).
RN   [2]
RP   FUNCTION.
RX   PubMed=23242138; DOI=10.1038/nature11723;
RA   Bondy-Denomy J., Pawluk A., Maxwell K.L., Davidson A.R.;
RT   "Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune
RT   system.";
RL   Nature 493:429-432(2013).
CC   -!- FUNCTION: Allows the phage to evade the CRISPR/Cas system type I-F.
CC       {ECO:0000269|PubMed:23242138}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY394005; AAQ94468.1; -; Genomic_DNA.
DR   RefSeq; NP_938237.1; NC_005178.1.
DR   PDB; 5UZ9; EM; 3.40 A; K=2-90.
DR   PDB; 5YHR; X-ray; 1.34 A; A/B=1-90.
DR   PDB; 6B47; EM; 3.20 A; K=1-90.
DR   PDBsum; 5UZ9; -.
DR   PDBsum; 5YHR; -.
DR   PDBsum; 6B47; -.
DR   SMR; Q6TM72; -.
DR   DIP; DIP-61768N; -.
DR   IntAct; Q6TM72; 5.
DR   GeneID; 2648149; -.
DR   KEGG; vg:2648149; -.
DR   Proteomes; UP000000875; Genome.
DR   GO; GO:0098672; P:inhibition of host CRISPR-cas system by virus; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   3D-structure; CRISPR-cas system evasion by virus; Host-virus interaction;
KW   Reference proteome.
FT   CHAIN           1..90
FT                   /note="Anti-CRISPR protein 30"
FT                   /id="PRO_0000433207"
FT   HELIX           1..5
FT                   /evidence="ECO:0007829|PDB:5YHR"
FT   HELIX           9..19
FT                   /evidence="ECO:0007829|PDB:5YHR"
FT   STRAND          21..26
FT                   /evidence="ECO:0007829|PDB:5YHR"
FT   STRAND          32..36
FT                   /evidence="ECO:0007829|PDB:5YHR"
FT   STRAND          40..47
FT                   /evidence="ECO:0007829|PDB:5YHR"
FT   STRAND          50..53
FT                   /evidence="ECO:0007829|PDB:5YHR"
FT   HELIX           58..67
FT                   /evidence="ECO:0007829|PDB:5YHR"
FT   HELIX           70..86
FT                   /evidence="ECO:0007829|PDB:5YHR"
SQ   SEQUENCE   90 AA;  9925 MW;  A0E50F77C90B3492 CRC64;
     MIAQQHKDTV AACEAAEAIA IAKDQVWDGE GYTKYTFDDN SVLIQSGTTQ YAMDADDADS
     IKGYADWLDD EARSAEASEI ERLLESVEEE