ACR3_ARATH
ID ACR3_ARATH Reviewed; 453 AA.
AC O49285; Q8LA88;
DT 07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 25-MAY-2022, entry version 137.
DE RecName: Full=ACT domain-containing protein ACR3 {ECO:0000305};
DE AltName: Full=Protein ACT DOMAIN REPEATS 3 {ECO:0000303|PubMed:12481063};
GN Name=ACR3 {ECO:0000303|PubMed:12481063};
GN OrderedLocusNames=At1g76990 {ECO:0000312|Araport:AT1G76990};
GN ORFNames=F22K20.9 {ECO:0000312|EMBL:AAC00631.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=12481063; DOI=10.1104/pp.007484;
RA Hsieh M.-H., Goodman H.M.;
RT "Molecular characterization of a novel gene family encoding ACT domain
RT repeat proteins in Arabidopsis.";
RL Plant Physiol. 130:1797-1806(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May bind amino acids. {ECO:0000303|PubMed:12481063}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, cotyledons, rosette and cauline
CC leaves, sepals, style, and pedicels and tips of young developing
CC siliques. {ECO:0000269|PubMed:12481063}.
CC -!- INDUCTION: Down-regulated by abscisic acid (ABA).
CC {ECO:0000269|PubMed:12481063}.
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DR EMBL; AF528059; AAM93428.1; -; mRNA.
DR EMBL; AC002291; AAC00631.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35917.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35918.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35919.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35920.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35921.1; -; Genomic_DNA.
DR EMBL; AF360322; AAK26032.1; -; mRNA.
DR EMBL; AY113891; AAM44939.1; -; mRNA.
DR EMBL; AK317369; BAH20041.1; -; mRNA.
DR EMBL; AY087972; AAM65519.1; -; mRNA.
DR PIR; H96798; H96798.
DR RefSeq; NP_001031289.1; NM_001036212.1.
DR RefSeq; NP_001117608.1; NM_001124136.2.
DR RefSeq; NP_565146.1; NM_106350.3.
DR RefSeq; NP_849896.1; NM_179565.2.
DR RefSeq; NP_849897.1; NM_179566.2.
DR AlphaFoldDB; O49285; -.
DR STRING; 3702.AT1G76990.3; -.
DR iPTMnet; O49285; -.
DR PaxDb; O49285; -.
DR PRIDE; O49285; -.
DR ProteomicsDB; 244652; -.
DR EnsemblPlants; AT1G76990.1; AT1G76990.1; AT1G76990.
DR EnsemblPlants; AT1G76990.2; AT1G76990.2; AT1G76990.
DR EnsemblPlants; AT1G76990.3; AT1G76990.3; AT1G76990.
DR EnsemblPlants; AT1G76990.4; AT1G76990.4; AT1G76990.
DR EnsemblPlants; AT1G76990.5; AT1G76990.5; AT1G76990.
DR GeneID; 844035; -.
DR Gramene; AT1G76990.1; AT1G76990.1; AT1G76990.
DR Gramene; AT1G76990.2; AT1G76990.2; AT1G76990.
DR Gramene; AT1G76990.3; AT1G76990.3; AT1G76990.
DR Gramene; AT1G76990.4; AT1G76990.4; AT1G76990.
DR Gramene; AT1G76990.5; AT1G76990.5; AT1G76990.
DR KEGG; ath:AT1G76990; -.
DR Araport; AT1G76990; -.
DR TAIR; locus:2025317; AT1G76990.
DR eggNOG; ENOG502R1FF; Eukaryota.
DR HOGENOM; CLU_031332_3_0_1; -.
DR InParanoid; O49285; -.
DR OMA; QLMHADV; -.
DR OrthoDB; 514448at2759; -.
DR PhylomeDB; O49285; -.
DR PRO; PR:O49285; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; O49285; baseline and differential.
DR Genevisible; O49285; AT.
DR GO; GO:0005829; C:cytosol; TAS:TAIR.
DR GO; GO:0016597; F:amino acid binding; ISS:TAIR.
DR InterPro; IPR040217; ACR1-12.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR PANTHER; PTHR31096; PTHR31096; 1.
DR Pfam; PF01842; ACT; 4.
DR SUPFAM; SSF55021; SSF55021; 3.
DR PROSITE; PS51671; ACT; 4.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat.
FT CHAIN 1..453
FT /note="ACT domain-containing protein ACR3"
FT /id="PRO_0000431457"
FT DOMAIN 37..112
FT /note="ACT 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT DOMAIN 130..212
FT /note="ACT 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT DOMAIN 266..341
FT /note="ACT 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT DOMAIN 344..423
FT /note="ACT 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
SQ SEQUENCE 453 AA; 50403 MW; 398854A709EFBFA4 CRC64;
MAKVYWPYFD PEYENLSSRI NPPSVSIDNT SCKECTLVKV DSMNKPGILL EVVQVLTDLD
LTITKAYISS DGGWFMDVFH VTDQQGNKVT DSKTIDYIEK VLGPKGHASA SQNTWPGKRV
GVHSLGDHTS IEIIARDRPG LLSEVSAVLA DLNINVVAAE AWTHNRRIAC VLYVNDNATS
RAVDDPERLS SMEEQLNNVL RGCEEQDEKF ARTSLSIGST HVDRRLHQMF FADRDYEAVT
KLDDSASCGF EPKITVEHCE EKGYSVINVS CEDRPKLMFD IVCTLTDMQY IVFHATISSS
GSHASQEYFI RHKDGCTLDT EGEKERVVKC LEAAIHRRVS EGWSLELCAK DRVGLLSEVT
RILREHGLSV SRAGVTTVGE QAVNVFYVKD ASGNPVDVKT IEALRGEIGH SMMIDFKNKV
PSRKWKEEGQ AGTGGGWAKT SFFFGNLLEK LLP
