ACR7_ARATH
ID ACR7_ARATH Reviewed; 449 AA.
AC Q8LJW1; O49659; Q8LPH4;
DT 07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=ACT domain-containing protein ACR7 {ECO:0000305};
DE AltName: Full=Protein ACT DOMAIN REPEATS 7 {ECO:0000303|PubMed:12481063};
GN Name=ACR7 {ECO:0000303|PubMed:12481063};
GN OrderedLocusNames=At4g22780 {ECO:0000312|Araport:AT4G22780};
GN ORFNames=T12H17.170 {ECO:0000312|EMBL:CAA16563.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=12481063; DOI=10.1104/pp.007484;
RA Hsieh M.-H., Goodman H.M.;
RT "Molecular characterization of a novel gene family encoding ACT domain
RT repeat proteins in Arabidopsis.";
RL Plant Physiol. 130:1797-1806(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF Clone.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May bind amino acids. {ECO:0000303|PubMed:12481063}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves and stems.
CC {ECO:0000269|PubMed:12481063}.
CC -!- INDUCTION: By cold stress. {ECO:0000269|PubMed:12481063}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA16563.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB79233.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF528063; AAM93432.1; -; mRNA.
DR EMBL; AL021635; CAA16563.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161558; CAB79233.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84657.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM67134.1; -; Genomic_DNA.
DR EMBL; AY099789; AAM20640.1; -; mRNA.
DR EMBL; BT029176; ABJ17111.1; -; mRNA.
DR PIR; T04573; T04573.
DR RefSeq; NP_001328982.1; NM_001341561.1.
DR RefSeq; NP_194009.2; NM_118407.5.
DR AlphaFoldDB; Q8LJW1; -.
DR STRING; 3702.AT4G22780.1; -.
DR PaxDb; Q8LJW1; -.
DR PRIDE; Q8LJW1; -.
DR ProteomicsDB; 244710; -.
DR EnsemblPlants; AT4G22780.1; AT4G22780.1; AT4G22780.
DR EnsemblPlants; AT4G22780.2; AT4G22780.2; AT4G22780.
DR GeneID; 828377; -.
DR Gramene; AT4G22780.1; AT4G22780.1; AT4G22780.
DR Gramene; AT4G22780.2; AT4G22780.2; AT4G22780.
DR KEGG; ath:AT4G22780; -.
DR Araport; AT4G22780; -.
DR TAIR; locus:2132609; AT4G22780.
DR eggNOG; ENOG502QS10; Eukaryota.
DR HOGENOM; CLU_031332_3_0_1; -.
DR InParanoid; Q8LJW1; -.
DR OMA; MIYVKDG; -.
DR OrthoDB; 696095at2759; -.
DR PhylomeDB; Q8LJW1; -.
DR PRO; PR:Q8LJW1; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q8LJW1; baseline and differential.
DR Genevisible; Q8LJW1; AT.
DR GO; GO:0005829; C:cytosol; ISS:TAIR.
DR GO; GO:0016597; F:amino acid binding; ISS:TAIR.
DR GO; GO:0071456; P:cellular response to hypoxia; HEP:TAIR.
DR InterPro; IPR040217; ACR1-12.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR PANTHER; PTHR31096; PTHR31096; 1.
DR Pfam; PF01842; ACT; 1.
DR SUPFAM; SSF55021; SSF55021; 4.
DR PROSITE; PS51671; ACT; 4.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat.
FT CHAIN 1..449
FT /note="ACT domain-containing protein ACR7"
FT /id="PRO_0000431461"
FT DOMAIN 34..112
FT /note="ACT 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT DOMAIN 115..197
FT /note="ACT 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT DOMAIN 246..322
FT /note="ACT 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT DOMAIN 324..404
FT /note="ACT 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT CONFLICT 420
FT /note="G -> E (in Ref. 4; AAM20640)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 449 AA; 50690 MW; BCD623B0359D3E11 CRC64;
MELSDCSNEY EKLVVRMNMP RVVIDNGVCP NSTVVKIDSA RSPGILLESV QLLTDMNLWI
KKAYISSDGK WNMDVFHVSD LNGDKLTDEN LIRYIEKSIE TSHYCKTEGY TGLTALELTG
TDRVGLLSEV FAVLADLECD VVEAKAWTHN GRIASMIYVK DGNSGTPIDG DSDRVQRVEG
QLRNLLKADD GYQNDTRTCV SYGGNTHMER RLHQRMFMDR DYEKKFDIEK SPIVSVQNLP
KRGYSVVNLQ CKDRMKLLFD VVCTLTDMAY IVFHAAIRTV GETAFLEFYV RHSDGHPVSS
EPERQRLIQC LQAAIERRTV KGVRLELCTA DRPGLLAEVT RILRENGLNI ARAEISTKDS
IARNVFYVTD ANGNLIDPEI IKSIREKIGI DDLSVKEPFP ISCREAVEKE QHIEPQDHQG
RYGGGTVLVS LGSLVMRNLY HLGLIKSYF
