36016_ASFB7
ID 36016_ASFB7 Reviewed; 311 AA.
AC P23163;
DT 01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT 11-NOV-2015, sequence version 2.
DT 23-FEB-2022, entry version 62.
DE RecName: Full=Protein MGF 360-16R;
GN OrderedLocusNames=BA71V-148; ORFNames=DP311R;
OS African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=10498;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2325203; DOI=10.1128/jvi.64.5.2073-2081.1990;
RA Gonzalez A., Calvo V., Almazan F., Almendral J.M., Ramirez J.C.,
RA de la Vega I., Blasco R., Vinuela E.;
RT "Multigene families in African swine fever virus: family 360.";
RL J. Virol. 64:2073-2081(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA Rodriguez J.F., Vinuela E.;
RT "Analysis of the complete nucleotide sequence of African swine fever
RT virus.";
RL Virology 208:249-278(1995).
RN [3]
RP SEQUENCE REVISION.
RA Rodriguez J.M., Salas M.L.;
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP FUNCTION.
RX PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA Rock D.L.;
RT "African swine fever virus multigene family 360 and 530 genes are novel
RT macrophage host range determinants.";
RL J. Virol. 75:3066-3076(2001).
RN [5]
RP INDUCTION.
RX PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA Dixon L., Werner F.;
RT "The African Swine Fever Virus Transcriptome.";
RL J. Virol. 94:0-0(2020).
CC -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC efficient virus replication in macrophages.
CC {ECO:0000269|PubMed:11238833}.
CC -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC {ECO:0000269|PubMed:32075923}.
CC -!- SIMILARITY: Belongs to the asfivirus MGF 360 family. {ECO:0000305}.
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DR EMBL; M57544; AAA42677.1; -; Genomic_DNA.
DR EMBL; U18466; AAA65374.2; -; Genomic_DNA.
DR PIR; E43680; E43680.
DR RefSeq; NP_042838.2; NC_001659.2.
DR GeneID; 22220374; -.
DR KEGG; vg:22220374; -.
DR Proteomes; UP000000624; Genome.
DR GO; GO:0042330; P:taxis; IEA:InterPro.
DR InterPro; IPR002595; ASFV_MGF360.
DR Pfam; PF01671; ASFV_360; 1.
PE 2: Evidence at transcript level;
KW Early protein; Reference proteome.
FT CHAIN 1..311
FT /note="Protein MGF 360-16R"
FT /id="PRO_0000221946"
FT CONFLICT 98
FT /note="A -> R (in Ref. 1; AAA42677)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 311 AA; 35489 MW; 5484240ABE16EAC3 CRC64;
MLSLQTIAKM AVATNTYSKY HYPILKVFGL WWKNSTLNGP IKICNHCNNI MVGEYPMCYN
HGMSLDIALI RAVKERNISL VQLFTEWGGN IDYGALCANT PSMQRLCKSL GAKPPKGRMY
MDALIHLSDT LNDNDLIRGY EIFDDNSVLD CVNLIRLKIM LTLKARIPLM EQLDQIALKQ
LLQRYWYAMA VQHNLTTAIH YFDNHIPNIK PFSLRCALYF NDPFKIHDAC RTVNMDPNEM
MNIACQQDLN FQSIYYSYIL GADINQAMLM SLKYGNLSNM WFCIDLGADA FKEAGALAGK
KKKSVTAHIR S