位置:首页 > 蛋白库 > CYC2_XENTR
CYC2_XENTR
ID   CYC2_XENTR              Reviewed;         105 AA.
AC   Q6PBF4; Q28I00;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Cytochrome c, testis-specific;
GN   Name=cyct; ORFNames=TEgg084a23.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Electron carrier protein. The oxidized form of the cytochrome
CC       c heme group can accept an electron from the heme group of the
CC       cytochrome c1 subunit of cytochrome reductase. Cytochrome c then
CC       transfers this electron to the cytochrome oxidase complex, the final
CC       protein carrier in the mitochondrial electron-transport chain (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion intermembrane space {ECO:0000250}.
CC       Note=Loosely associated with the inner membrane. {ECO:0000250}.
CC   -!- PTM: Binds 1 heme c group covalently per subunit. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cytochrome c family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAJ81709.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   -!- WEB RESOURCE: Name=Protein Spotlight; Note=Life shuttle - Issue 76 of
CC       November 2006;
CC       URL="https://web.expasy.org/spotlight/back_issues/076";
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR760663; CAJ81709.1; ALT_INIT; mRNA.
DR   EMBL; BC059740; AAH59740.1; -; mRNA.
DR   RefSeq; NP_988895.1; NM_203564.1.
DR   RefSeq; XP_012819873.1; XM_012964419.2.
DR   AlphaFoldDB; Q6PBF4; -.
DR   SMR; Q6PBF4; -.
DR   STRING; 8364.ENSXETP00000049267; -.
DR   PaxDb; Q6PBF4; -.
DR   DNASU; 394490; -.
DR   Ensembl; ENSXETT00000049267; ENSXETP00000049267; ENSXETG00000027531.
DR   GeneID; 394490; -.
DR   KEGG; xtr:394490; -.
DR   CTD; 54205; -.
DR   Xenbase; XB-GENE-971588; cycs.
DR   eggNOG; KOG3453; Eukaryota.
DR   HOGENOM; CLU_060944_3_0_1; -.
DR   InParanoid; Q6PBF4; -.
DR   OrthoDB; 1533604at2759; -.
DR   PhylomeDB; Q6PBF4; -.
DR   TreeFam; TF300226; -.
DR   Reactome; R-XTR-111457; Release of apoptotic factors from the mitochondria.
DR   Reactome; R-XTR-111458; Formation of apoptosome.
DR   Reactome; R-XTR-2151201; Transcriptional activation of mitochondrial biogenesis.
DR   Reactome; R-XTR-3299685; Detoxification of Reactive Oxygen Species.
DR   Reactome; R-XTR-5620971; Pyroptosis.
DR   Reactome; R-XTR-611105; Respiratory electron transport.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000027531; Expressed in gastrula and 13 other tissues.
DR   GO; GO:0005758; C:mitochondrial intermembrane space; IBA:GO_Central.
DR   GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IBA:GO_Central.
DR   GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IBA:GO_Central.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IBA:GO_Central.
DR   Gene3D; 1.10.760.10; -; 1.
DR   InterPro; IPR009056; Cyt_c-like_dom.
DR   InterPro; IPR036909; Cyt_c-like_dom_sf.
DR   InterPro; IPR002327; Cyt_c_1A/1B.
DR   PANTHER; PTHR11961; PTHR11961; 1.
DR   Pfam; PF00034; Cytochrom_C; 1.
DR   PRINTS; PR00604; CYTCHRMECIAB.
DR   SUPFAM; SSF46626; SSF46626; 1.
DR   PROSITE; PS51007; CYTC; 1.
PE   3: Inferred from homology;
KW   Acetylation; Electron transport; Heme; Iron; Metal-binding; Mitochondrion;
KW   Reference proteome; Respiratory chain; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..105
FT                   /note="Cytochrome c, testis-specific"
FT                   /id="PRO_0000269464"
FT   BINDING         15
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /note="covalent"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   BINDING         18
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /note="covalent"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   BINDING         19
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   BINDING         81
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   MOD_RES         2
FT                   /note="N-acetylglycine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   105 AA;  11635 MW;  18C9BB300FB02436 CRC64;
     MGDAEKGKKI FVQKCSQCHT VEKGGKHKTG PNLHGLFGRK TGQAEGFSYT DANKNKGIVW
     DEGTLLEYLE NPKKYIPGTK MIFAGIKKKG ERQDLIAYLK QSTSS
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024