ID   CYCG_CERS4              Reviewed;         296 AA.
AC   Q53143; Q3J2P3;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Diheme cytochrome c-type;
GN   Name=cycG; OrderedLocusNames=RHOS4_13730; ORFNames=RSP_2784;
OS   Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS   31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS   sphaeroides).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Cereibacter.
OX   NCBI_TaxID=272943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7543472; DOI=10.1128/jb.177.15.4311-4320.1995;
RA   Flory J.E., Donohue T.J.;
RT   "Organization and expression of the Rhodobacter sphaeroides cycFG operon.";
RL   J. Bacteriol. 177:4311-4320(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203
RC   / NCIMB 8253 / ATH 2.4.1.;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C.,
RA   Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.;
RT   "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Particularly expressed when cells generate energy via aerobic
CC       respiration.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein.
CC   -!- PTM: Binds 2 heme c groups covalently per subunit.
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DR   EMBL; L36880; AAD09146.1; -; Genomic_DNA.
DR   EMBL; CP000143; ABA78941.1; -; Genomic_DNA.
DR   RefSeq; WP_011337741.1; NZ_CP030271.1.
DR   RefSeq; YP_352842.1; NC_007493.2.
DR   AlphaFoldDB; Q53143; -.
DR   STRING; 272943.RSP_2784; -.
DR   EnsemblBacteria; ABA78941; ABA78941; RSP_2784.
DR   KEGG; rsp:RSP_2784; -.
DR   PATRIC; fig|272943.9.peg.1708; -.
DR   eggNOG; COG2010; Bacteria.
DR   OMA; GDYSFED; -.
DR   PhylomeDB; Q53143; -.
DR   Proteomes; UP000002703; Chromosome 1.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.760.10; -; 2.
DR   InterPro; IPR009056; Cyt_c-like_dom.
DR   InterPro; IPR036909; Cyt_c-like_dom_sf.
DR   Pfam; PF00034; Cytochrom_C; 2.
DR   SUPFAM; SSF46626; SSF46626; 2.
DR   PROSITE; PS51007; CYTC; 2.
PE   4: Predicted;
KW   Cell membrane; Electron transport; Heme; Iron; Membrane; Metal-binding;
KW   Reference proteome; Transport.
FT   CHAIN           1..296
FT                   /note="Diheme cytochrome c-type"
FT                   /id="PRO_0000108443"
FT   BINDING         52
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /ligand_label="1"
FT                   /note="covalent"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   BINDING         55
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /ligand_label="1"
FT                   /note="covalent"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   BINDING         56
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /ligand_label="1"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   BINDING         202
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /ligand_label="2"
FT                   /note="covalent"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   BINDING         205
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /ligand_label="2"
FT                   /note="covalent"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   BINDING         206
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /ligand_label="2"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
SQ   SEQUENCE   296 AA;  31727 MW;  4C4A9D8F695B5BFD CRC64;
     MRRSLTAGLA LVLIAGAAGL WLTRPVKSDP ELFAGLTGEA SRGERIFWAG GCASCHAAPD
     ASGEARLVLS GGERLTTDFG TFVVPNISPD PDHGIGGWTV ADLDSALRHG TSPERSHYYP
     SFPYTSYAHV EPQDVADLKA FLDTLPPSDR ADEPHDLAFP FNQRIILGGW KLLAGGPSWI
     VEGDLAPEEE RGRYLVEGLG HCGECHTPRN GLGLRDKSRW LAGGPNPEGR GTIPNITPAK
     LDWSAGDIAE YLSSGFTPDY DSAGGQMADV VRNTSQLPDE DRRAIAAYLK RVPAIE