ID   CYCH_PSEAE              Reviewed;         407 AA.
AC   Q9I3M9;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Cytochrome c-type biogenesis protein CycH;
GN   Name=cycH; OrderedLocusNames=PA1483;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Required for the biogenesis of c-type cytochromes. Possible
CC       subunit of a heme lyase (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}; Periplasmic side {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CycH family. {ECO:0000305}.
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DR   EMBL; AE004091; AAG04872.1; -; Genomic_DNA.
DR   PIR; D83460; D83460.
DR   RefSeq; NP_250174.1; NC_002516.2.
DR   RefSeq; WP_003083145.1; NZ_QZGE01000005.1.
DR   AlphaFoldDB; Q9I3M9; -.
DR   SMR; Q9I3M9; -.
DR   STRING; 287.DR97_540; -.
DR   PaxDb; Q9I3M9; -.
DR   PRIDE; Q9I3M9; -.
DR   EnsemblBacteria; AAG04872; AAG04872; PA1483.
DR   GeneID; 881742; -.
DR   KEGG; pae:PA1483; -.
DR   PATRIC; fig|208964.12.peg.1534; -.
DR   PseudoCAP; PA1483; -.
DR   HOGENOM; CLU_036074_2_1_6; -.
DR   InParanoid; Q9I3M9; -.
DR   OMA; IMQQMIG; -.
DR   PhylomeDB; Q9I3M9; -.
DR   BioCyc; PAER208964:G1FZ6-1509-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR017560; Cyt_c_biogenesis_CcmI.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   SMART; SM00028; TPR; 2.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   TIGRFAMs; TIGR03142; cytochro_ccmI; 1.
DR   PROSITE; PS50005; TPR; 2.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Cytochrome c-type biogenesis; Membrane;
KW   Reference proteome; Repeat; TPR repeat; Transmembrane; Transmembrane helix.
FT   CHAIN           1..407
FT                   /note="Cytochrome c-type biogenesis protein CycH"
FT                   /id="PRO_0000287763"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REPEAT          150..183
FT                   /note="TPR 1"
FT   REPEAT          221..254
FT                   /note="TPR 2"
FT   REGION          388..407
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   407 AA;  43294 MW;  DAB5477D1BA7028B CRC64;
     MIDFWLAAGL LLLAALAFLL IPLLRGRRAQ AEEDRTALNV ALYQERIAEL AGQQAAGTLT
     AEQLENGRAE AARELLADTE GSGEERSSRL GRAVPLVAAL LVPLVALGLY LHWGASDKVE
     LAREFAQAPH SMEEMTARLE RAVQAQPDSA QGWYFLGRTY MTQERGADAA RAFERAAELS
     GRQPEVLGQW AQALYFSGGK KMTAQIKALA DEALKGDPAE VTTLGLLGIA AFEEQRYADA
     IGFWERLVSV LPNEDPARSA IQGGIQRARE RMTEAGQTPP APAAPAAAGV TLTVKVDISD
     AVKGQVKADD SVFVFARAVG GPPMPLAVKR LTVADLPAEV SLSDADAMMP QLKLSGFPQV
     ELVARVSRAG NAISGEWIGR GKPLSTAQSS AQALTIDGPD QPQAARP