CYCH_PSEFL
ID CYCH_PSEFL Reviewed; 327 AA.
AC P52223;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Cytochrome c-type biogenesis protein CycH;
GN Name=cycH;
OS Pseudomonas fluorescens.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=294;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=09906;
RA Yang C.H., Azad H.R., Cooksey D.A.;
RL Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the biogenesis of c-type cytochromes. Possible
CC subunit of a heme lyase (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}; Periplasmic side {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CycH family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U44827; AAC44229.1; -; Genomic_DNA.
DR AlphaFoldDB; P52223; -.
DR SMR; P52223; -.
DR STRING; 690597.JH730938_gene2124; -.
DR eggNOG; COG4235; Bacteria.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR017560; Cyt_c_biogenesis_CcmI.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF48452; SSF48452; 1.
DR TIGRFAMs; TIGR03142; cytochro_ccmI; 1.
DR PROSITE; PS50005; TPR; 2.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Cytochrome c-type biogenesis; Membrane;
KW Repeat; TPR repeat; Transmembrane; Transmembrane helix.
FT CHAIN 1..327
FT /note="Cytochrome c-type biogenesis protein CycH"
FT /id="PRO_0000201573"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 150..183
FT /note="TPR 1"
FT REPEAT 221..254
FT /note="TPR 2"
SQ SEQUENCE 327 AA; 36113 MW; A9737B81B7D3E7BB CRC64;
MIDFWLAAGL LLLIALSFLL IPVLRGRRAQ REEDRTALNV ALYQERVAEL QVQQDEGVLN
AAQLDTGRAE AARELLADTE GVEKPRESRL GKPLPFLAAF LVPVLGVVLY LHYGASDKVE
LTREFSQPPV SMADMTQRLE RAAAAQPDSA EGLYFLGRAY MAQDRSADAA KVFERTVALA
GRQPELLGQW AQAQYFADNK QWSPKVQALT DEALKLDPKE VTSLGLLGIA AFEGQRYQEA
IDYWNRLLAQ LPPQDNSRVA LQGGIDRAAE KLKESGGTVA HKTVMTVRVD LSAEAKAKTL
PSDSVVHLRP RRLRPTGTVG GQARYRR