CYCLF_ANNCH
ID CYCLF_ANNCH Reviewed; 9 AA.
AC P85002;
DT 17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 1.
DT 11-DEC-2019, entry version 12.
DE RecName: Full=Cyclopeptide F;
OS Annona cherimola (Custard apple) (Cherimoya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Magnoliidae; Magnoliales; Annonaceae;
OC Annonoideae; Annoneae; Annona.
OX NCBI_TaxID=49314;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, CROSS-LINK, FUNCTION, AND MASS SPECTROMETRY.
RC TISSUE=Seed {ECO:0000269|PubMed:16040066};
RX PubMed=16040066; DOI=10.1016/j.phytochem.2005.06.011;
RA Wele A., Zhang Y., Brouard J.-P., Pousset J.-L., Bodo B.;
RT "Two cyclopeptides from the seeds of Annona cherimola.";
RL Phytochemistry 66:2376-2380(2005).
CC -!- FUNCTION: Probably participates in a plant defense mechanism. Has
CC cytotoxic activity against human nasopharyngeal carcinoma with an
CC IC(50) of 60 nM. {ECO:0000269|PubMed:16040066}.
CC -!- PTM: This is a cyclic peptide. {ECO:0000269|PubMed:16040066}.
CC -!- MASS SPECTROMETRY: Mass=960; Method=Electrospray;
CC Evidence={ECO:0000269|PubMed:16040066};
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DR GO; GO:0006952; P:defense response; IDA:UniProtKB.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Plant defense.
FT PEPTIDE 1..9
FT /note="Cyclopeptide F"
FT /evidence="ECO:0000269|PubMed:16040066"
FT /id="PRO_0000253928"
FT CROSSLNK 1..9
FT /note="Cyclopeptide (Pro-Met)"
SQ SEQUENCE 9 AA; 978 MW; 3897673B50587698 CRC64;
PGMGIYLPM