CYCP_RHOCA
ID CYCP_RHOCA Reviewed; 129 AA.
AC P00147;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Cytochrome c';
OS Rhodobacter capsulatus (Rhodopseudomonas capsulata).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC Rhodobacteraceae; Rhodobacter.
OX NCBI_TaxID=1061;
RN [1]
RP PROTEIN SEQUENCE.
RC STRAIN=SP7;
RX PubMed=6273892; DOI=10.1073/pnas.78.11.6854;
RA Ambler R.P., Bartsch R.G., Daniel M., Kamen M.D., McLellan L., Meyer T.E.,
RA van Beeumen J.;
RT "Amino acid sequences of bacterial cytochromes c' and c-556.";
RL Proc. Natl. Acad. Sci. U.S.A. 78:6854-6857(1981).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS).
RC STRAIN=M110;
RX PubMed=8612077; DOI=10.1038/nsb0596-459;
RA Tahirov T.H., Misaki S., Meyer T.E., Cusanovich M.A., Higuchi Y.,
RA Yasuoka N.;
RT "Concerted movement of side chains in the haem vicinity observed on ligand
RT binding in cytochrome c' from rhodobacter capsulatus.";
RL Nat. Struct. Biol. 3:459-464(1996).
RN [3]
RP X-RAY CRYSTALLOGRAPHY (1.72 ANGSTROMS).
RC STRAIN=M110;
RX PubMed=8676382; DOI=10.1006/jmbi.1996.0333;
RA Tahirov T.H., Misaki S., Meyer T.E., Cusanovich M.A., Higuchi Y.,
RA Yasuoka N.;
RT "High-resolution crystal structures of two polymorphs of cytochrome c' from
RT the purple phototrophic bacterium rhodobacter capsulatus.";
RL J. Mol. Biol. 259:467-479(1996).
RN [4]
RP X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS).
RC STRAIN=ATCC 23782 / St Louis;
RX PubMed=15299853; DOI=10.1107/s0907444997005805;
RA Tahirov T.H., Misaki S., Meyer T.E., Cusanovich M.A., Higuchi Y.,
RA Yasuoka N.;
RT "Structure of Cytochrome c' from Rhodobacter capsulatus strain St Louis: an
RT unusual molecular association induced by bridging Zn ions.";
RL Acta Crystallogr. D 53:658-664(1997).
CC -!- FUNCTION: Cytochrome c' is the most widely occurring bacterial c-type
CC cytochrome. Cytochromes c' are high-spin proteins and the heme has no
CC sixth ligand. Their exact function is not known.
CC -!- PTM: Binds 1 heme group per subunit.
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DR PIR; A00140; CCRFPP.
DR PDB; 1CPQ; X-ray; 1.72 A; A=1-129.
DR PDB; 1CPR; X-ray; 2.10 A; A=1-129.
DR PDB; 1EKY; NMR; -; A=1-129.
DR PDB; 1NBB; X-ray; 2.40 A; A/B=1-129.
DR PDB; 1RCP; X-ray; 2.00 A; A/B=1-129.
DR PDBsum; 1CPQ; -.
DR PDBsum; 1CPR; -.
DR PDBsum; 1EKY; -.
DR PDBsum; 1NBB; -.
DR PDBsum; 1RCP; -.
DR AlphaFoldDB; P00147; -.
DR SMR; P00147; -.
DR DrugBank; DB01826; N-Butyl Isocyanide.
DR EvolutionaryTrace; P00147; -.
DR GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR InterPro; IPR010980; Cyt_c/b562.
DR InterPro; IPR002321; Cyt_c_II.
DR InterPro; IPR012127; Cyt_c_prime.
DR InterPro; IPR015984; Cyt_c_prime_subgr.
DR Pfam; PF01322; Cytochrom_C_2; 1.
DR PIRSF; PIRSF000027; Cytc_c_prime; 1.
DR PRINTS; PR00608; CYTCHROMECII.
DR SUPFAM; SSF47175; SSF47175; 1.
DR PROSITE; PS51009; CYTCII; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; Electron transport; Heme; Iron;
KW Metal-binding; Transport.
FT CHAIN 1..129
FT /note="Cytochrome c'"
FT /id="PRO_0000108371"
FT BINDING 118
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /note="covalent"
FT BINDING 121
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /note="covalent"
FT BINDING 122
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT VARIANT 19
FT /note="K -> G (in strain: M110 and St Louis)"
FT VARIANT 30
FT /note="S -> A (in strain: M110 and St Louis)"
FT VARIANT 38
FT /note="A -> V (in strain: M110 and St Louis)"
FT VARIANT 42
FT /note="A -> K (in strain: M110 and St Louis)"
FT VARIANT 76
FT /note="T -> A (in strain: M110 and St Louis)"
FT VARIANT 79
FT /note="A -> D (in strain: M110 and St Louis)"
FT VARIANT 89
FT /note="N -> H (in strain: M110 and St Louis)"
FT VARIANT 90
FT /note="D -> E (in strain: M110)"
FT VARIANT 93..94
FT /note="AE -> GA (in strain: M110 and St Louis)"
FT VARIANT 104..105
FT /note="AT -> GA (in strain: M110 and St Louis)"
FT HELIX 3..29
FT /evidence="ECO:0007829|PDB:1CPQ"
FT HELIX 33..46
FT /evidence="ECO:0007829|PDB:1CPQ"
FT HELIX 52..54
FT /evidence="ECO:0007829|PDB:1CPQ"
FT TURN 61..63
FT /evidence="ECO:0007829|PDB:1CPQ"
FT TURN 65..67
FT /evidence="ECO:0007829|PDB:1CPQ"
FT HELIX 73..76
FT /evidence="ECO:0007829|PDB:1CPQ"
FT HELIX 78..101
FT /evidence="ECO:0007829|PDB:1CPQ"
FT HELIX 104..125
FT /evidence="ECO:0007829|PDB:1CPQ"
SQ SEQUENCE 129 AA; 13206 MW; C2092D8549F8F808 CRC64;
ADTKEVLEAR EAYFKSLGKS MKAMTGVAKS FDAEAAKAEA AALEKILATD VAPLFPAGTS
STDLPGQTEA KAAIWTNMAD FGAKGKAMND AGAEVIAAAN AGDATAFGAA LQKLGGTCKA
CHDDYREED
