ID   CYHR1_DANRE             Reviewed;         375 AA.
AC   Q08CH8;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Cysteine and histidine-rich protein 1;
GN   Name=cyhr1; ORFNames=zgc:153061;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CYHR1 family. {ECO:0000305}.
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DR   EMBL; BC124233; AAI24234.1; -; mRNA.
DR   RefSeq; NP_001070208.1; NM_001076740.1.
DR   AlphaFoldDB; Q08CH8; -.
DR   STRING; 7955.ENSDARP00000081094; -.
DR   PaxDb; Q08CH8; -.
DR   GeneID; 767773; -.
DR   KEGG; dre:767773; -.
DR   CTD; 50626; -.
DR   ZFIN; ZDB-GENE-060929-720; cyhr1.
DR   eggNOG; KOG3002; Eukaryota.
DR   InParanoid; Q08CH8; -.
DR   OrthoDB; 1174688at2759; -.
DR   PhylomeDB; Q08CH8; -.
DR   PRO; PR:Q08CH8; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; -; 2.
DR   InterPro; IPR039338; CYHR1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR23059; PTHR23059; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..375
FT                   /note="Cysteine and histidine-rich protein 1"
FT                   /id="PRO_0000328855"
FT   ZN_FING         82..127
FT                   /note="RING-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   ZN_FING         140..196
FT                   /note="TRAF-type"
FT   REGION          36..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..65
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   375 AA;  41780 MW;  68D6AB312070DFA7 CRC64;
     MELGVAAAPG SSSSGLGVGP VGGALDAGPA SAGLAGIQEE SGVRRDGSVG EADPDAPPKK
     RVRLQEGEAG KLEERLYSVL CCTVCLDLPK ASVYQCTNGH LMCAGCFIHL LADSRLKEEQ
     ATCPNCRCEI SKSLCCRNLA VEKAVSELPS ECSYCLKQFP RSGLDRHQTE ECQDRVTQCK
     YKRIGCPWQG PFHELSAHEA ECCHPSKTGM ELMGILDEMD QSHRRELQLY NSIFSLLCFE
     KIGFTEVQFR PYRTDDFITR LYYETPRFTV LNQTWVLKAR VNDSERNPNL SCKRTLAFQL
     ILKSKVNSAL ECSFLLLKGP YEDIKIKPVI QHHVFSNDAN ETEYAPLPIC DSVECNKLLA
     AKNINLRLFI FQIQK