36019_ASFB7
ID 36019_ASFB7 Reviewed; 363 AA.
AC P23164;
DT 01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 2.
DT 23-FEB-2022, entry version 79.
DE RecName: Full=Protein MGF 360-19R;
GN OrderedLocusNames=BA71V-156; ORFNames=DP363R;
OS African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=10498;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2325203; DOI=10.1128/jvi.64.5.2073-2081.1990;
RA Gonzalez A., Calvo V., Almazan F., Almendral J.M., Ramirez J.C.,
RA de la Vega I., Blasco R., Vinuela E.;
RT "Multigene families in African swine fever virus: family 360.";
RL J. Virol. 64:2073-2081(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA Rodriguez J.F., Vinuela E.;
RT "Analysis of the complete nucleotide sequence of African swine fever
RT virus.";
RL Virology 208:249-278(1995).
RN [3]
RP FUNCTION.
RX PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA Rock D.L.;
RT "African swine fever virus multigene family 360 and 530 genes are novel
RT macrophage host range determinants.";
RL J. Virol. 75:3066-3076(2001).
RN [4]
RP INDUCTION.
RX PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA Dixon L., Werner F.;
RT "The African Swine Fever Virus Transcriptome.";
RL J. Virol. 94:0-0(2020).
CC -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC efficient virus replication in macrophages.
CC {ECO:0000269|PubMed:11238833}.
CC -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC {ECO:0000269|PubMed:32075923}.
CC -!- SIMILARITY: Belongs to the asfivirus MGF 360 family. {ECO:0000305}.
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DR EMBL; M57545; AAA42678.1; -; Genomic_DNA.
DR EMBL; U18466; AAA65382.1; -; Genomic_DNA.
DR PIR; F43680; F43680.
DR RefSeq; NP_042846.1; NC_001659.2.
DR GeneID; 22220382; -.
DR KEGG; vg:22220382; -.
DR Proteomes; UP000000624; Genome.
DR GO; GO:0042330; P:taxis; IEA:InterPro.
DR InterPro; IPR002595; ASFV_MGF360.
DR Pfam; PF01671; ASFV_360; 1.
PE 2: Evidence at transcript level;
KW ANK repeat; Early protein; Reference proteome.
FT CHAIN 1..363
FT /note="Protein MGF 360-19R"
FT /id="PRO_0000221951"
FT REPEAT 66..98
FT /note="ANK"
FT CONFLICT 241
FT /note="M -> T (in Ref. 1; AAA42678)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 363 AA; 42353 MW; 4841A8165647BFE3 CRC64;
MPSTLQVLAK KVLALGEHKE NEHISREYYY HILKCCGLWW HEAPIILCFD GSEQMMIKTP
IFEEGILLNT ALMKAVQENN YELINLFTEW GANINYGLIS INTEHARDLC RKLGAKEMLE
RNEVIQIVFK TLDDITSSNI ILCHELFTNN PLLENVNMGE MRMIIHWRMK NLTNLLLNND
SISEILTKFW YGIAVKYNLK DAIQYFYQRF MDFNEWRVTC ALSFNNVNDL HKMYITEKVH
MNNDEMMNLA CSIQDRNLST IYYCFLLGAN INQAMLTSVL NYNIFNLFFC IDLGADAFEE
GKTLAKQKGY NEIVEILSLD IIYSPNTDFS SKIEPEHISS LLKNFYPKNL FAFDRCNPGL
YYS