CYOB_HAEIN
ID CYOB_HAEIN Reviewed; 378 AA.
AC P45020;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Probable cytochrome oxidase subunit 2;
DE EC=1.10.3.-;
DE AltName: Full=Cytochrome oxidase subunit II;
GN OrderedLocusNames=HI_1075;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- FUNCTION: Probable cytochrome oxidase subunit.
CC -!- SUBUNIT: Heterodimer of subunits I and II. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- MISCELLANEOUS: Probable ortholog of the ancestor of E.coli AppB/CydB.
CC -!- SIMILARITY: Belongs to the cytochrome ubiquinol oxidase subunit 2
CC family. {ECO:0000305}.
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DR EMBL; L42023; AAC22731.1; -; Genomic_DNA.
DR PIR; D64181; D64181.
DR RefSeq; NP_439231.1; NC_000907.1.
DR RefSeq; WP_010869126.1; NC_000907.1.
DR AlphaFoldDB; P45020; -.
DR SMR; P45020; -.
DR STRING; 71421.HI_1075; -.
DR EnsemblBacteria; AAC22731; AAC22731; HI_1075.
DR KEGG; hin:HI_1075; -.
DR PATRIC; fig|71421.8.peg.1117; -.
DR eggNOG; COG1294; Bacteria.
DR HOGENOM; CLU_049294_0_0_6; -.
DR OMA; FLWGVAF; -.
DR PhylomeDB; P45020; -.
DR BioCyc; HINF71421:G1GJ1-1109-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0070069; C:cytochrome complex; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009055; F:electron transfer activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016682; F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor; IBA:GO_Central.
DR GO; GO:0019646; P:aerobic electron transport chain; IBA:GO_Central.
DR InterPro; IPR003317; Cyt-d_oxidase_su2.
DR PANTHER; PTHR43141; PTHR43141; 1.
DR Pfam; PF02322; Cyt_bd_oxida_II; 1.
DR PIRSF; PIRSF000267; Cyt_oxidse_sub2; 1.
DR TIGRFAMs; TIGR00203; cydB; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Electron transport; Heme; Iron;
KW Membrane; Metal-binding; Oxidoreductase; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..378
FT /note="Probable cytochrome oxidase subunit 2"
FT /id="PRO_0000183929"
FT TOPO_DOM 1..8
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 9..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 29..79
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 80..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 100..122
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 143..164
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 165..184
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 185..205
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 206..224
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 225..261
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 262..281
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 282..291
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 292..311
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 312..335
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 336..355
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 356..378
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 378 AA; 42067 MW; 2760245B44FE3473 CRC64;
MIDYEFLRFI WWVLVIVLLI GFSVTDGFDM GVTALLPVIG KKEVERRIMI NTIAPHWDGN
QVWLLTAGGA IFAAWPIVYA VSFSGFYIAL VLVLAALFLR PLGFEYRAKI DNPTWRSVWD
WGLFAGGFVP ALVFGVAFGN LLQGVPFHFN ELTQVTYTGS FFELLNPFAL LCGVISLSML
VTHGANWLQM KTTEALRDRA RTVSQIGSIV TLIAFVLAGV WLYSKDGYVV TSTIDHFAPS
SPMNKEVAVE TGAWFRNFNE MPILWIFPAL AVVAALLNAA FSKANRCGFA FFFSALTMAG
VIITAAVSMF PFVMPSSSHP EQSLLMWDST SSELTLTLML IFAVVFVVIA LAYTIWSYSK
MFGRLDANFI DKNKHSLY
