CYOC_PSEAE
ID CYOC_PSEAE Reviewed; 209 AA.
AC Q9I425;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Cytochrome bo(3) ubiquinol oxidase subunit 3;
DE AltName: Full=Cytochrome o ubiquinol oxidase subunit 3;
DE Short=Cytochrome o subunit 3;
DE AltName: Full=Oxidase bo(3) subunit 3;
DE AltName: Full=Ubiquinol oxidase polypeptide III;
DE AltName: Full=Ubiquinol oxidase subunit 3;
GN Name=cyoC; OrderedLocusNames=PA1319;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: Cytochrome bo(3) ubiquinol terminal oxidase is the component
CC of the aerobic respiratory chain of E.coli that predominates when cells
CC are grown at high aeration. Has proton pump activity across the
CC membrane in addition to electron transfer, pumping 2 protons/electron
CC (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Heterooctamer of two A chains, two B chains, two C chains and
CC two D chains. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 3 family.
CC {ECO:0000305}.
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DR EMBL; AE004091; AAG04708.1; -; Genomic_DNA.
DR PIR; F83480; F83480.
DR RefSeq; NP_250010.1; NC_002516.2.
DR RefSeq; WP_003086858.1; NZ_QZGE01000005.1.
DR AlphaFoldDB; Q9I425; -.
DR SMR; Q9I425; -.
DR STRING; 287.DR97_475; -.
DR PaxDb; Q9I425; -.
DR PRIDE; Q9I425; -.
DR DNASU; 881595; -.
DR EnsemblBacteria; AAG04708; AAG04708; PA1319.
DR GeneID; 881595; -.
DR KEGG; pae:PA1319; -.
DR PATRIC; fig|208964.12.peg.1371; -.
DR PseudoCAP; PA1319; -.
DR HOGENOM; CLU_044071_3_0_6; -.
DR InParanoid; Q9I425; -.
DR OMA; FLDLLWV; -.
DR PhylomeDB; Q9I425; -.
DR BioCyc; PAER208964:G1FZ6-1344-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0009319; C:cytochrome o ubiquinol oxidase complex; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0009486; F:cytochrome bo3 ubiquinol oxidase activity; IBA:GO_Central.
DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR GO; GO:0009055; F:electron transfer activity; IBA:GO_Central.
DR GO; GO:0015453; F:oxidoreduction-driven active transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0019646; P:aerobic electron transport chain; IBA:GO_Central.
DR GO; GO:0009060; P:aerobic respiration; IBA:GO_Central.
DR GO; GO:0015990; P:electron transport coupled proton transport; IBA:GO_Central.
DR CDD; cd02863; Ubiquinol_oxidase_III; 1.
DR Gene3D; 1.20.120.80; -; 1.
DR InterPro; IPR024791; Cyt_c/ubiquinol_Oxase_su3.
DR InterPro; IPR000298; Cyt_c_oxidase-like_su3.
DR InterPro; IPR035973; Cyt_c_oxidase_su3-like_sf.
DR InterPro; IPR013833; Cyt_c_oxidase_su3_a-hlx.
DR InterPro; IPR014206; Cyt_c_ubiqinol_oxidase_su3.
DR InterPro; IPR033946; Ubiquinol_oxase_su3_dom.
DR PANTHER; PTHR11403; PTHR11403; 1.
DR Pfam; PF00510; COX3; 1.
DR SUPFAM; SSF81452; SSF81452; 1.
DR TIGRFAMs; TIGR02842; CyoC; 1.
DR PROSITE; PS50253; COX3; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Electron transport; Membrane;
KW Oxidoreductase; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..209
FT /note="Cytochrome bo(3) ubiquinol oxidase subunit 3"
FT /id="PRO_0000287757"
FT TOPO_DOM 1..29
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 51..72
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 94..102
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 124..143
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 165..186
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 208..209
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 209 AA; 22847 MW; 5E5503607D080876 CRC64;
MSTAVLNKHL ADAHEVGHDH DHAHDSGGNT VFGFWLYLMT DCVLFASVFA TYAVLVHHTA
GGPSGKDIFE LPYVLVETAI LLVSSCTYGL AMLSAHKGAK GQAIAWLGVT FLLGAAFIGM
EINEFHHLIA EGFGPSRSAF LSSFFTLVGM HGLHVSAGLL WMLVLMAQIW TRGLTAQNNT
RMMCLSLFWH FLDIVWICVF TVVYLMGAL
