ID   CYOC_PSEPU              Reviewed;         207 AA.
AC   Q9WWR3;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Cytochrome bo(3) ubiquinol oxidase subunit 3;
DE   AltName: Full=Cytochrome o ubiquinol oxidase subunit 3;
DE            Short=Cytochrome o subunit 3;
DE   AltName: Full=Oxidase bo(3) subunit 3;
DE   AltName: Full=Ubiquinol oxidase polypeptide III;
DE   AltName: Full=Ubiquinol oxidase subunit 3;
GN   Name=cyoC;
OS   Pseudomonas putida (Arthrobacter siderocapsulatus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=303;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=IH-2000;
RX   PubMed=9868765; DOI=10.1111/j.1574-6968.1998.tb13321.x;
RA   Hirayama H., Takami H., Inoue A., Horikoshi K.;
RT   "Isolation and characterization of toluene-sensitive mutants from
RT   Pseudomonas putida IH-2000.";
RL   FEMS Microbiol. Lett. 169:219-225(1998).
CC   -!- FUNCTION: Cytochrome bo(3) ubiquinol terminal oxidase is the component
CC       of the aerobic respiratory chain of E.coli that predominates when cells
CC       are grown at high aeration. Has proton pump activity across the
CC       membrane in addition to electron transfer, pumping 2 protons/electron
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heterooctamer of two A chains, two B chains, two C chains and
CC       two D chains. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 3 family.
CC       {ECO:0000305}.
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DR   EMBL; AB016787; BAA76358.1; -; Genomic_DNA.
DR   RefSeq; WP_025337745.1; NZ_JOME01000023.1.
DR   AlphaFoldDB; Q9WWR3; -.
DR   SMR; Q9WWR3; -.
DR   eggNOG; COG1845; Bacteria.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009486; F:cytochrome bo3 ubiquinol oxidase activity; IEA:InterPro.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR   GO; GO:0019646; P:aerobic electron transport chain; IEA:InterPro.
DR   CDD; cd02863; Ubiquinol_oxidase_III; 1.
DR   Gene3D; 1.20.120.80; -; 1.
DR   InterPro; IPR024791; Cyt_c/ubiquinol_Oxase_su3.
DR   InterPro; IPR000298; Cyt_c_oxidase-like_su3.
DR   InterPro; IPR035973; Cyt_c_oxidase_su3-like_sf.
DR   InterPro; IPR013833; Cyt_c_oxidase_su3_a-hlx.
DR   InterPro; IPR014206; Cyt_c_ubiqinol_oxidase_su3.
DR   InterPro; IPR033946; Ubiquinol_oxase_su3_dom.
DR   PANTHER; PTHR11403; PTHR11403; 1.
DR   Pfam; PF00510; COX3; 1.
DR   SUPFAM; SSF81452; SSF81452; 1.
DR   TIGRFAMs; TIGR02842; CyoC; 1.
DR   PROSITE; PS50253; COX3; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Electron transport; Membrane;
KW   Oxidoreductase; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..207
FT                   /note="Cytochrome bo(3) ubiquinol oxidase subunit 3"
FT                   /id="PRO_0000183899"
FT   TOPO_DOM        1..26
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        27..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        48..70
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        92..99
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        121..141
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        163..185
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        207
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   207 AA;  22814 MW;  43F00A40C8A577CD CRC64;
     MSSQVMHGAA HGHDHGHDDH HHDSGQMTVL GFWLYLMTDC ILFASLFATY AVLSGSFAGG
     PSGHDIFQLD FVAVETLFLL LSSITFGFAM LKMFDGKKAG VLGWLAVTFL FGAGFIAMEI
     YEFHHLIAEG FGPQRSGFLS GFFALVGTHG LHVTAGLIWM AIMMYQINKH GITPTAKTRM
     SCLSLFWHFL DVVWICVFTV VYLLGVL