CYOD_BUCAI
ID CYOD_BUCAI Reviewed; 105 AA.
AC P57541;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2000, sequence version 1.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=Cytochrome bo(3) ubiquinol oxidase subunit 4;
DE AltName: Full=Cytochrome o ubiquinol oxidase subunit 4;
DE Short=Cytochrome o subunit 4;
DE AltName: Full=Oxidase bo(3) subunit 4;
DE AltName: Full=Ubiquinol oxidase polypeptide IV;
DE AltName: Full=Ubiquinol oxidase subunit 4;
GN Name=cyoD; OrderedLocusNames=BU469;
OS Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS pisum symbiotic bacterium).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Buchnera.
OX NCBI_TaxID=107806;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=APS;
RX PubMed=10993077; DOI=10.1038/35024074;
RA Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT sp. APS.";
RL Nature 407:81-86(2000).
CC -!- FUNCTION: Cytochrome bo(3) ubiquinol terminal oxidase is the component
CC of the aerobic respiratory chain of E.coli that predominates when cells
CC are grown at high aeration. Has proton pump activity across the
CC membrane in addition to electron transfer, pumping 2 protons/electron
CC (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Heterooctamer of two A chains, two B chains, two C chains and
CC two D chains. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the cytochrome c oxidase bacterial subunit 4
CC family. {ECO:0000305}.
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DR EMBL; BA000003; BAB13166.1; -; Genomic_DNA.
DR RefSeq; NP_240280.1; NC_002528.1.
DR RefSeq; WP_009874421.1; NC_002528.1.
DR AlphaFoldDB; P57541; -.
DR SMR; P57541; -.
DR STRING; 107806.10039132; -.
DR EnsemblBacteria; BAB13166; BAB13166; BAB13166.
DR KEGG; buc:BU469; -.
DR PATRIC; fig|107806.10.peg.478; -.
DR eggNOG; COG3125; Bacteria.
DR HOGENOM; CLU_140945_1_1_6; -.
DR OMA; IVVHMVF; -.
DR Proteomes; UP000001806; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009486; F:cytochrome bo3 ubiquinol oxidase activity; IEA:InterPro.
DR GO; GO:0015990; P:electron transport coupled proton transport; IEA:InterPro.
DR InterPro; IPR005171; Cyt_c_oxidase_su4_prok.
DR InterPro; IPR014210; Cyt_o_ubiqinol_oxidase_su4.
DR Pfam; PF03626; COX4_pro; 1.
DR TIGRFAMs; TIGR02847; CyoD; 1.
PE 3: Inferred from homology;
KW Cell membrane; Electron transport; Membrane; Oxidoreductase;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..105
FT /note="Cytochrome bo(3) ubiquinol oxidase subunit 4"
FT /id="PRO_0000183913"
FT TOPO_DOM 1..14
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 36..45
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 67..75
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 97..105
FT /note="Extracellular"
FT /evidence="ECO:0000255"
SQ SEQUENCE 105 AA; 12459 MW; 4037743B48E784F6 CRC64;
MSSFLNFNMN KEMKSYLLGF LFSSLLTTLP FLLAIEKFFC SEVNYIIFLL CAISQIIIHF
VYFLHLSFDP EERWNLITLL FVIIIIFIVV FGSIWIMFNL NHNTM
