CYOD_BUCAP
ID CYOD_BUCAP Reviewed; 108 AA.
AC Q8K996;
DT 08-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2002, sequence version 2.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Cytochrome bo(3) ubiquinol oxidase subunit 4;
DE AltName: Full=Cytochrome o ubiquinol oxidase subunit 4;
DE Short=Cytochrome o subunit 4;
DE AltName: Full=Oxidase bo(3) subunit 4;
DE AltName: Full=Ubiquinol oxidase polypeptide IV;
DE AltName: Full=Ubiquinol oxidase subunit 4;
GN Name=cyoD; OrderedLocusNames=BUsg_453;
OS Buchnera aphidicola subsp. Schizaphis graminum (strain Sg).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Buchnera.
OX NCBI_TaxID=198804;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sg;
RX PubMed=12089438; DOI=10.1126/science.1071278;
RA Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT "50 million years of genomic stasis in endosymbiotic bacteria.";
RL Science 296:2376-2379(2002).
CC -!- FUNCTION: Cytochrome bo(3) ubiquinol terminal oxidase is the component
CC of the aerobic respiratory chain of E.coli that predominates when cells
CC are grown at high aeration. Has proton pump activity across the
CC membrane in addition to electron transfer, pumping 2 protons/electron
CC (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Heterooctamer of two A chains, two B chains, two C chains and
CC two D chains. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the cytochrome c oxidase bacterial subunit 4
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM67996.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AE013218; AAM67996.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_011053963.1; NC_004061.1.
DR AlphaFoldDB; Q8K996; -.
DR SMR; Q8K996; -.
DR STRING; 198804.BUsg_453; -.
DR EnsemblBacteria; AAM67996; AAM67996; BUsg_453.
DR KEGG; bas:BUsg_453; -.
DR eggNOG; COG3125; Bacteria.
DR HOGENOM; CLU_140945_1_1_6; -.
DR OMA; IVVHMVF; -.
DR OrthoDB; 2088013at2; -.
DR Proteomes; UP000000416; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009486; F:cytochrome bo3 ubiquinol oxidase activity; IEA:InterPro.
DR GO; GO:0015990; P:electron transport coupled proton transport; IEA:InterPro.
DR InterPro; IPR005171; Cyt_c_oxidase_su4_prok.
DR InterPro; IPR014210; Cyt_o_ubiqinol_oxidase_su4.
DR Pfam; PF03626; COX4_pro; 1.
DR TIGRFAMs; TIGR02847; CyoD; 1.
PE 3: Inferred from homology;
KW Cell membrane; Electron transport; Membrane; Oxidoreductase; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..108
FT /note="Cytochrome bo(3) ubiquinol oxidase subunit 4"
FT /id="PRO_0000183914"
FT TOPO_DOM 1..16
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 38..46
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 68..77
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 99..108
FT /note="Extracellular"
FT /evidence="ECO:0000255"
SQ SEQUENCE 108 AA; 12995 MW; 97263707ABD3E79C CRC64;
MNKYKKIKNN FDKEKKSYIV GFLFSLFLTI IPFFCTLNHL FSRKINFFVI LLCALSQIII
HFIYFLHLDF SKKNSWNIIS LLFILIIVFI IVFGSIWIMY NLNHHVIL
