ID   CYOD_BUCBP              Reviewed;         100 AA.
AC   Q89AA6;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Cytochrome bo(3) ubiquinol oxidase subunit 4;
DE   AltName: Full=Cytochrome o ubiquinol oxidase subunit 4;
DE            Short=Cytochrome o subunit 4;
DE   AltName: Full=Oxidase bo(3) subunit 4;
DE   AltName: Full=Ubiquinol oxidase polypeptide IV;
DE   AltName: Full=Ubiquinol oxidase subunit 4;
GN   Name=cyoD; OrderedLocusNames=bbp_414;
OS   Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=224915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bp;
RX   PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- FUNCTION: Cytochrome bo(3) ubiquinol terminal oxidase is the component
CC       of the aerobic respiratory chain of E.coli that predominates when cells
CC       are grown at high aeration. Has proton pump activity across the
CC       membrane in addition to electron transfer, pumping 2 protons/electron
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heterooctamer of two A chains, two B chains, two C chains and
CC       two D chains. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase bacterial subunit 4
CC       family. {ECO:0000305}.
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DR   EMBL; AE016826; AAO27124.1; -; Genomic_DNA.
DR   RefSeq; WP_011091525.1; NC_004545.1.
DR   AlphaFoldDB; Q89AA6; -.
DR   SMR; Q89AA6; -.
DR   STRING; 224915.bbp_414; -.
DR   EnsemblBacteria; AAO27124; AAO27124; bbp_414.
DR   GeneID; 56471089; -.
DR   KEGG; bab:bbp_414; -.
DR   eggNOG; COG3125; Bacteria.
DR   HOGENOM; CLU_140945_1_1_6; -.
DR   OMA; KWNIISI; -.
DR   Proteomes; UP000000601; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Cell membrane; Electron transport; Membrane; Oxidoreductase;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..100
FT                   /note="Cytochrome bo(3) ubiquinol oxidase subunit 4"
FT                   /id="PRO_0000183915"
FT   TOPO_DOM        1..9
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        10..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        33..36
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        60..68
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        91..100
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   100 AA;  11923 MW;  7C8F79C5079532E1 CRC64;
     MLKNRYLKYL FILILLSILS IMPIFAIIYR IFSRNYLYAF IIVCLFFQIL AHIKFFLNLD
     FSLEQRWKLI SVIFSLVVGL IILLGSIWVI KNLNNNLCIM