CYOD_ECO57
ID CYOD_ECO57 Reviewed; 109 AA.
AC P0ABJ7; P18403; P77116;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Cytochrome bo(3) ubiquinol oxidase subunit 4;
DE AltName: Full=Cytochrome o ubiquinol oxidase subunit 4;
DE Short=Cytochrome o subunit 4;
DE AltName: Full=Oxidase bo(3) subunit 4;
DE AltName: Full=Ubiquinol oxidase chain D;
DE AltName: Full=Ubiquinol oxidase polypeptide IV;
DE AltName: Full=Ubiquinol oxidase subunit 4;
GN Name=cyoD; OrderedLocusNames=Z0532, ECs0483;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Cytochrome bo(3) ubiquinol terminal oxidase is the component
CC of the aerobic respiratory chain of E.coli that predominates when cells
CC are grown at high aeration. Has proton pump activity across the
CC membrane in addition to electron transfer, pumping 2 protons/electron
CC (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Heterooctamer of two A chains, two B chains, two C chains and
CC two D chains. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the cytochrome c oxidase bacterial subunit 4
CC family. {ECO:0000305}.
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DR EMBL; AE005174; AAG54779.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB33906.1; -; Genomic_DNA.
DR PIR; C90689; C90689.
DR PIR; G85539; G85539.
DR RefSeq; NP_308510.1; NC_002695.1.
DR RefSeq; WP_000019869.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; P0ABJ7; -.
DR SMR; P0ABJ7; -.
DR STRING; 155864.EDL933_0499; -.
DR EnsemblBacteria; AAG54779; AAG54779; Z0532.
DR EnsemblBacteria; BAB33906; BAB33906; ECs_0483.
DR GeneID; 66671269; -.
DR GeneID; 914585; -.
DR KEGG; ece:Z0532; -.
DR KEGG; ecs:ECs_0483; -.
DR PATRIC; fig|386585.9.peg.584; -.
DR eggNOG; COG3125; Bacteria.
DR HOGENOM; CLU_140945_1_0_6; -.
DR OMA; IVVHMVF; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009486; F:cytochrome bo3 ubiquinol oxidase activity; IEA:InterPro.
DR GO; GO:0015990; P:electron transport coupled proton transport; IEA:InterPro.
DR InterPro; IPR005171; Cyt_c_oxidase_su4_prok.
DR InterPro; IPR014210; Cyt_o_ubiqinol_oxidase_su4.
DR Pfam; PF03626; COX4_pro; 1.
DR TIGRFAMs; TIGR02847; CyoD; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Electron transport; Membrane;
KW Oxidoreductase; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..109
FT /note="Cytochrome bo(3) ubiquinol oxidase subunit 4"
FT /id="PRO_0000183911"
FT TOPO_DOM 1..17
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 18..36
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 37..45
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 46..64
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 65..80
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 81..99
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 100..109
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
SQ SEQUENCE 109 AA; 12029 MW; E2DBE23C893724BA CRC64;
MSHSTDHSGA SHGSVKTYMT GFILSIILTV IPFWMVMTGA ASPAVILGTI LAMAVVQVLV
HLVCFLHMNT KSDEGWNMTA FVFTVLIIAI LVVGSIWIMW NLNYNMMMH
