ID   CYOD_PSEPU              Reviewed;         110 AA.
AC   Q9WWR4;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Cytochrome bo(3) ubiquinol oxidase subunit 4;
DE   AltName: Full=Cytochrome o ubiquinol oxidase subunit 4;
DE            Short=Cytochrome o subunit 4;
DE   AltName: Full=Oxidase bo(3) subunit 4;
DE   AltName: Full=Ubiquinol oxidase polypeptide IV;
DE   AltName: Full=Ubiquinol oxidase subunit 4;
GN   Name=cyoD;
OS   Pseudomonas putida (Arthrobacter siderocapsulatus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=303;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=IH-2000;
RX   PubMed=9868765; DOI=10.1111/j.1574-6968.1998.tb13321.x;
RA   Hirayama H., Takami H., Inoue A., Horikoshi K.;
RT   "Isolation and characterization of toluene-sensitive mutants from
RT   Pseudomonas putida IH-2000.";
RL   FEMS Microbiol. Lett. 169:219-225(1998).
CC   -!- FUNCTION: Cytochrome bo(3) ubiquinol terminal oxidase is the component
CC       of the aerobic respiratory chain of E.coli that predominates when cells
CC       are grown at high aeration. Has proton pump activity across the
CC       membrane in addition to electron transfer, pumping 2 protons/electron
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heterooctamer of two A chains, two B chains, two C chains and
CC       two D chains. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase bacterial subunit 4
CC       family. {ECO:0000305}.
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DR   EMBL; AB016787; BAA76359.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9WWR4; -.
DR   SMR; Q9WWR4; -.
DR   STRING; 1240350.AMZE01000009_gene4207; -.
DR   eggNOG; COG3125; Bacteria.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009486; F:cytochrome bo3 ubiquinol oxidase activity; IEA:InterPro.
DR   GO; GO:0015990; P:electron transport coupled proton transport; IEA:InterPro.
DR   InterPro; IPR005171; Cyt_c_oxidase_su4_prok.
DR   InterPro; IPR014210; Cyt_o_ubiqinol_oxidase_su4.
DR   Pfam; PF03626; COX4_pro; 1.
DR   TIGRFAMs; TIGR02847; CyoD; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Electron transport; Membrane;
KW   Oxidoreductase; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..110
FT                   /note="Cytochrome bo(3) ubiquinol oxidase subunit 4"
FT                   /id="PRO_0000183916"
FT   TOPO_DOM        1..18
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        40..46
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        68..78
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        100..110
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   110 AA;  12376 MW;  074ED0BE854FC0C9 CRC64;
     MANAHDTHHE GNHGSVKSYM IGFILSIILT AIPFGLAMSP SLPKNLTVLI IVAMAVIQVV
     VHLVYFLHMD RSKEQRNNVW TFLFTTLVIA LLVGLSLWIM FSIHFEMLAK