ID   CYR1A_XENLA             Reviewed;         365 AA.
AC   Q6GNX1; Q0IHK8;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 2.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Cysteine and histidine-rich protein 1-A;
GN   Name=cyhr1-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CYHR1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH73380.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAI23108.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC073380; AAH73380.1; ALT_INIT; mRNA.
DR   EMBL; BC123107; AAI23108.1; ALT_INIT; mRNA.
DR   AlphaFoldDB; Q6GNX1; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.30.40.10; -; 2.
DR   InterPro; IPR039338; CYHR1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR001293; Znf_TRAF.
DR   PANTHER; PTHR23059; PTHR23059; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
DR   PROSITE; PS50145; ZF_TRAF; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..365
FT                   /note="Cysteine and histidine-rich protein 1-A"
FT                   /id="PRO_0000328856"
FT   ZN_FING         72..117
FT                   /note="RING-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   ZN_FING         113..186
FT                   /note="TRAF-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00207"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        11
FT                   /note="L -> M (in Ref. 1; AAI23108)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   365 AA;  41545 MW;  34FA32804D6B0E5A CRC64;
     MSEEREAPGP LASSSAGLGA EVGQEEVPGG AGPARLLLLP SDSDGPPKKR LRSEAEPGSV
     RLEERLYSVL CCTVCLDLPK ASVYQCTNGH LMCAGCFIHL LADSRLKEEQ ATCPNCRCEI
     SKSLCCRNLA VEKAVSELPS DCGFCLKQFP RSLLERHKKE ECQDRVTQCK YKRIGCPWEG
     PYHELTVHES ECCHPTKTGN ELMEILDEMD QTHKKEMQLY NSIFSLLSFE KIGYTEVQFR
     PYRTDDFITR LYYETPRFTV LNQTWVLKAR VNDSERNPNL SCKRTLSFQL ILKSKINSPM
     ECSFLLLKGP YDDVKIHPVI YHFVFTNENN ETEYVPLPII DSVECNKLLA AKNINLRLFI
     FQIQK