ID   CYSE_BUCAP              Reviewed;         261 AA.
AC   P32003;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 118.
DE   RecName: Full=Serine acetyltransferase;
DE            Short=SAT;
DE            EC=2.3.1.30;
GN   Name=cysE; OrderedLocusNames=BUsg_051;
OS   Buchnera aphidicola subsp. Schizaphis graminum (strain Sg).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=198804;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1398077; DOI=10.1016/0378-1119(92)90074-y;
RA   Lai C.-Y., Baumann P.;
RT   "Sequence analysis of a DNA fragment from Buchnera aphidicola (an
RT   endosymbiont of aphids) containing genes homologous to dnaG, rpoD, cysE,
RT   and secB.";
RL   Gene 119:113-118(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sg;
RX   PubMed=12089438; DOI=10.1126/science.1071278;
RA   Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA   Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT   "50 million years of genomic stasis in endosymbiotic bacteria.";
RL   Science 296:2376-2379(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + L-serine = CoA + O-acetyl-L-serine;
CC         Xref=Rhea:RHEA:24560, ChEBI:CHEBI:33384, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57288, ChEBI:CHEBI:58340; EC=2.3.1.30;
CC   -!- PATHWAY: Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine
CC       from L-serine: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000305}.
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DR   EMBL; M90644; AAA73232.1; -; Genomic_DNA.
DR   EMBL; AE013218; AAM67622.1; -; Genomic_DNA.
DR   PIR; JC1293; JC1293.
DR   AlphaFoldDB; P32003; -.
DR   SMR; P32003; -.
DR   STRING; 198804.BUsg_051; -.
DR   EnsemblBacteria; AAM67622; AAM67622; BUsg_051.
DR   KEGG; bas:BUsg_051; -.
DR   eggNOG; COG1045; Bacteria.
DR   HOGENOM; CLU_051638_0_1_6; -.
DR   OMA; DVIMHDR; -.
DR   UniPathway; UPA00136; UER00199.
DR   Proteomes; UP000000416; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009001; F:serine O-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   CDD; cd03354; LbH_SAT; 1.
DR   Gene3D; 1.10.3130.10; -; 1.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR018357; Hexapep_transf_CS.
DR   InterPro; IPR045304; LbH_SAT.
DR   InterPro; IPR010493; Ser_AcTrfase_N.
DR   InterPro; IPR042122; Ser_AcTrfase_N_sf.
DR   InterPro; IPR005881; Ser_O-AcTrfase.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   Pfam; PF00132; Hexapep; 1.
DR   Pfam; PF06426; SATase_N; 1.
DR   SMART; SM00971; SATase_N; 1.
DR   SUPFAM; SSF51161; SSF51161; 1.
DR   TIGRFAMs; TIGR01172; cysE; 1.
DR   PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Amino-acid biosynthesis; Cysteine biosynthesis; Cytoplasm;
KW   Repeat; Transferase.
FT   CHAIN           1..261
FT                   /note="Serine acetyltransferase"
FT                   /id="PRO_0000068667"
SQ   SEQUENCE   261 AA;  28914 MW;  DC02685464A25944 CRC64;
     MCSLEELELW NMIKHKAQKI LKKEPILSNF YQKSILNHKK LSHSLSCILS DKLSTSMISE
     KDIYNIFNKI YANNISIINS VVKDIKAASQ RDPVVKHYLT PLLYLKGFHA LEAYRLSHYL
     WNIKRYELSA YLQSRISTVF SVDIHPAASI GSGIMLDHAT GIVIGEGVII ENDVSIFHSV
     TLGGTGSNTG KNRHPIIRKN VTIGAGAKIL GNIEVGQGVK VGAGSIVLKN IPPFVTVVGV
     PAKIIKKIKN SNKNLFQKEK K