ID   CYSE_SYNY3              Reviewed;         249 AA.
AC   P74089; Q55209;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Serine acetyltransferase;
DE            Short=SAT;
DE            EC=2.3.1.30;
GN   Name=cysE; OrderedLocusNames=slr1348;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Sakamoto T., Wada H., Nishida I., Ohta H., Murata N.;
RT   "Sequence analysis of a DNA fragment from Synechocystis PCC6803 containing
RT   genes homologous to cysE (serine acetyltransferase) and pgi (glucose-6-
RT   phosphate isomerase).";
RL   Plant Mol. Biol. 29:187-187(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + L-serine = CoA + O-acetyl-L-serine;
CC         Xref=Rhea:RHEA:24560, ChEBI:CHEBI:33384, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57288, ChEBI:CHEBI:58340; EC=2.3.1.30;
CC   -!- PATHWAY: Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine
CC       from L-serine: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000305}.
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DR   EMBL; D13777; BAA02919.1; -; Genomic_DNA.
DR   EMBL; BA000022; BAA18167.1; -; Genomic_DNA.
DR   PIR; S75606; S75606.
DR   AlphaFoldDB; P74089; -.
DR   SMR; P74089; -.
DR   IntAct; P74089; 2.
DR   STRING; 1148.1653252; -.
DR   PaxDb; P74089; -.
DR   EnsemblBacteria; BAA18167; BAA18167; BAA18167.
DR   KEGG; syn:slr1348; -.
DR   eggNOG; COG1045; Bacteria.
DR   InParanoid; P74089; -.
DR   OMA; GDDVMLY; -.
DR   PhylomeDB; P74089; -.
DR   UniPathway; UPA00136; UER00199.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0031470; C:carboxysome; IEA:UniProt.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0009001; F:serine O-acetyltransferase activity; IBA:GO_Central.
DR   GO; GO:0043886; F:structural constituent of carboxysome; IEA:UniProt.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   CDD; cd03354; LbH_SAT; 1.
DR   Gene3D; 1.10.3130.10; -; 1.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR018357; Hexapep_transf_CS.
DR   InterPro; IPR045304; LbH_SAT.
DR   InterPro; IPR042122; Ser_AcTrfase_N_sf.
DR   InterPro; IPR005881; Ser_O-AcTrfase.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   Pfam; PF00132; Hexapep; 2.
DR   PIRSF; PIRSF000441; CysE; 1.
DR   SUPFAM; SSF51161; SSF51161; 1.
DR   TIGRFAMs; TIGR01172; cysE; 1.
DR   PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Amino-acid biosynthesis; Cysteine biosynthesis; Cytoplasm;
KW   Reference proteome; Repeat; Transferase.
FT   CHAIN           1..249
FT                   /note="Serine acetyltransferase"
FT                   /id="PRO_0000068687"
FT   CONFLICT        80
FT                   /note="I -> S (in Ref. 1; BAA02919)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   249 AA;  27336 MW;  ED5EC58D659DCFBB CRC64;
     MLNSLIADFR IIFERDPAAR NWLEVLFCYP GLQALLIHRF SHRLYTLGLP FFPRLMSHLA
     RFFTGIEIHP GAQIGQGVFI DHGMGVVIGE TAIVGDYSLI YQGVTLGGTG KESGKRHPTL
     GENVVVGAGA KVLGNIAIGD NVRIGAGSVV LRDVPADFTV VGVPGRMVHP SGERVNPLEH
     GKLPDSEGKV IRLLLERIEL LEQQVATLQQ QQSEQAWESD YRSCSETDRE PVLCRLGDRE
     IEEFLGGTL