ID   3602L_ASFB7             Reviewed;         362 AA.
AC   P23166;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Protein MGF 360-2L;
GN   OrderedLocusNames=BA71V-004; ORFNames=KP362L;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2325203; DOI=10.1128/jvi.64.5.2073-2081.1990;
RA   Gonzalez A., Calvo V., Almazan F., Almendral J.M., Ramirez J.C.,
RA   de la Vega I., Blasco R., Vinuela E.;
RT   "Multigene families in African swine fever virus: family 360.";
RL   J. Virol. 64:2073-2081(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [3]
RP   FUNCTION.
RX   PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA   Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA   Rock D.L.;
RT   "African swine fever virus multigene family 360 and 530 genes are novel
RT   macrophage host range determinants.";
RL   J. Virol. 75:3066-3076(2001).
RN   [4]
RP   FUNCTION.
RX   PubMed=14747550; DOI=10.1128/jvi.78.4.1858-1864.2004;
RA   Afonso C.L., Piccone M.E., Zaffuto K.M., Neilan J., Kutish G.F., Lu Z.,
RA   Balinsky C.A., Gibb T.R., Bean T.J., Zsak L., Rock D.L.;
RT   "African swine fever virus multigene family 360 and 530 genes affect host
RT   interferon response.";
RL   J. Virol. 78:1858-1864(2004).
RN   [5]
RP   FUNCTION.
RX   PubMed=14963141; DOI=10.1128/jvi.78.5.2445-2453.2004;
RA   Burrage T.G., Lu Z., Neilan J.G., Rock D.L., Zsak L.;
RT   "African swine fever virus multigene family 360 genes affect virus
RT   replication and generalization of infection in Ornithodoros porcinus
RT   ticks.";
RL   J. Virol. 78:2445-2453(2004).
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages. {ECO:0000250,
CC       ECO:0000269|PubMed:11238833, ECO:0000269|PubMed:14747550,
CC       ECO:0000269|PubMed:14963141}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 360 family. {ECO:0000305}.
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DR   EMBL; M57546; AAA42682.1; -; Genomic_DNA.
DR   EMBL; U18466; AAA65239.1; -; Genomic_DNA.
DR   PIR; B43680; B43680.
DR   RefSeq; NP_042703.1; NC_001659.2.
DR   SMR; P23166; -.
DR   GeneID; 22220393; -.
DR   KEGG; vg:22220393; -.
DR   Proteomes; UP000000624; Genome.
DR   GO; GO:0042330; P:taxis; IEA:InterPro.
DR   InterPro; IPR002595; ASFV_MGF360.
DR   Pfam; PF01671; ASFV_360; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..362
FT                   /note="Protein MGF 360-2L"
FT                   /id="PRO_0000221950"
SQ   SEQUENCE   362 AA;  42639 MW;  F8F53A6BF1A218B8 CRC64;
     MSTPLSLQAL AKKILATQHI SKNHYFILKY CGLWWHGAPI MFSTNEDNQL MIKSAIFKDG
     LELNLALMKA VQENNYDLIE LFTEWGADIN SSLVTVNTEH TWNFCRELGA KILNEMDIVQ
     IFYKIHRIKT SSNIILCHKL LSNNPLFQNI EELKIIICCF LEKISINFIL NEITLNEMLA
     RLWYSMAVRY HLTEAIQYFY QRYRHFKDWR LICGLSFNNV SDLHEIYHIK KVDMNIDEMM
     YLACMRDSNF LTIFYCFVLG ANINRAMVTS VKNFYTNNLF FCIDLGANAF EESLELAKQK
     NHDILVEILS FKDFYNSNVS LLSLKTTDPE KINALLKNYR SKNIMRYKKL CPKIIRWARF
     II