3602L_ASFB7
ID 3602L_ASFB7 Reviewed; 362 AA.
AC P23166;
DT 01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1991, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Protein MGF 360-2L;
GN OrderedLocusNames=BA71V-004; ORFNames=KP362L;
OS African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=10498;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2325203; DOI=10.1128/jvi.64.5.2073-2081.1990;
RA Gonzalez A., Calvo V., Almazan F., Almendral J.M., Ramirez J.C.,
RA de la Vega I., Blasco R., Vinuela E.;
RT "Multigene families in African swine fever virus: family 360.";
RL J. Virol. 64:2073-2081(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA Rodriguez J.F., Vinuela E.;
RT "Analysis of the complete nucleotide sequence of African swine fever
RT virus.";
RL Virology 208:249-278(1995).
RN [3]
RP FUNCTION.
RX PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA Rock D.L.;
RT "African swine fever virus multigene family 360 and 530 genes are novel
RT macrophage host range determinants.";
RL J. Virol. 75:3066-3076(2001).
RN [4]
RP FUNCTION.
RX PubMed=14747550; DOI=10.1128/jvi.78.4.1858-1864.2004;
RA Afonso C.L., Piccone M.E., Zaffuto K.M., Neilan J., Kutish G.F., Lu Z.,
RA Balinsky C.A., Gibb T.R., Bean T.J., Zsak L., Rock D.L.;
RT "African swine fever virus multigene family 360 and 530 genes affect host
RT interferon response.";
RL J. Virol. 78:1858-1864(2004).
RN [5]
RP FUNCTION.
RX PubMed=14963141; DOI=10.1128/jvi.78.5.2445-2453.2004;
RA Burrage T.G., Lu Z., Neilan J.G., Rock D.L., Zsak L.;
RT "African swine fever virus multigene family 360 genes affect virus
RT replication and generalization of infection in Ornithodoros porcinus
RT ticks.";
RL J. Virol. 78:2445-2453(2004).
CC -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC efficient virus replication in macrophages. {ECO:0000250,
CC ECO:0000269|PubMed:11238833, ECO:0000269|PubMed:14747550,
CC ECO:0000269|PubMed:14963141}.
CC -!- SIMILARITY: Belongs to the asfivirus MGF 360 family. {ECO:0000305}.
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DR EMBL; M57546; AAA42682.1; -; Genomic_DNA.
DR EMBL; U18466; AAA65239.1; -; Genomic_DNA.
DR PIR; B43680; B43680.
DR RefSeq; NP_042703.1; NC_001659.2.
DR SMR; P23166; -.
DR GeneID; 22220393; -.
DR KEGG; vg:22220393; -.
DR Proteomes; UP000000624; Genome.
DR GO; GO:0042330; P:taxis; IEA:InterPro.
DR InterPro; IPR002595; ASFV_MGF360.
DR Pfam; PF01671; ASFV_360; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..362
FT /note="Protein MGF 360-2L"
FT /id="PRO_0000221950"
SQ SEQUENCE 362 AA; 42639 MW; F8F53A6BF1A218B8 CRC64;
MSTPLSLQAL AKKILATQHI SKNHYFILKY CGLWWHGAPI MFSTNEDNQL MIKSAIFKDG
LELNLALMKA VQENNYDLIE LFTEWGADIN SSLVTVNTEH TWNFCRELGA KILNEMDIVQ
IFYKIHRIKT SSNIILCHKL LSNNPLFQNI EELKIIICCF LEKISINFIL NEITLNEMLA
RLWYSMAVRY HLTEAIQYFY QRYRHFKDWR LICGLSFNNV SDLHEIYHIK KVDMNIDEMM
YLACMRDSNF LTIFYCFVLG ANINRAMVTS VKNFYTNNLF FCIDLGANAF EESLELAKQK
NHDILVEILS FKDFYNSNVS LLSLKTTDPE KINALLKNYR SKNIMRYKKL CPKIIRWARF
II