CYSP1_VASCU
ID CYSP1_VASCU Reviewed; 43 AA.
AC P32954;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1993, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Cysteine proteinase 1;
DE EC=3.4.22.-;
DE AltName: Full=CC-I;
DE AltName: Full=Cysteine proteinase I;
DE Flags: Fragment;
OS Vasconcellea cundinamarcensis (Mountain papaya) (Carica candamarcensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Caricaceae; Vasconcellea.
OX NCBI_TaxID=35926;
RN [1]
RP PROTEIN SEQUENCE.
RC TISSUE=Latex;
RX PubMed=8216902; DOI=10.1515/bchm3.1993.374.7-12.501;
RA Walreavens V., Jaziri M., van Beeumen J., Schnek A.G., Kleinschmidt T.,
RA Looze Y.;
RT "Isolation and preliminary characterization of the cysteine-proteinases
RT from the latex of Carica candamarcensis Hook.";
RL Biol. Chem. Hoppe-Seyler 374:501-506(1993).
CC -!- SIMILARITY: Belongs to the peptidase C1 family. {ECO:0000255|PROSITE-
CC ProRule:PRU10088, ECO:0000255|PROSITE-ProRule:PRU10089,
CC ECO:0000255|PROSITE-ProRule:PRU10090}.
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DR AlphaFoldDB; P32954; -.
DR SMR; P32954; -.
DR MEROPS; C01.019; -.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR Pfam; PF00112; Peptidase_C1; 1.
DR SUPFAM; SSF54001; SSF54001; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Hydrolase; Protease; Thiol protease.
FT CHAIN 1..>43
FT /note="Cysteine proteinase 1"
FT /id="PRO_0000050564"
FT ACT_SITE 25
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10088,
FT ECO:0000255|PROSITE-ProRule:PRU10089, ECO:0000255|PROSITE-
FT ProRule:PRU10090"
FT NON_TER 43
SQ SEQUENCE 43 AA; 4550 MW; F35F0EB9ED972991 CRC64;
IVASIDWRQK GAVTPVRNQG SCGSCWTFSS VAAVEGIIKI RGT