ID   CYSP2_VASCU             Reviewed;          43 AA.
AC   P32955;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Cysteine proteinase 2;
DE            EC=3.4.22.-;
DE   AltName: Full=CC-II;
DE   AltName: Full=Cysteine proteinase II;
DE   Flags: Fragment;
OS   Vasconcellea cundinamarcensis (Mountain papaya) (Carica candamarcensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Caricaceae; Vasconcellea.
OX   NCBI_TaxID=35926;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Latex;
RX   PubMed=8216902; DOI=10.1515/bchm3.1993.374.7-12.501;
RA   Walreavens V., Jaziri M., van Beeumen J., Schnek A.G., Kleinschmidt T.,
RA   Looze Y.;
RT   "Isolation and preliminary characterization of the cysteine-proteinases
RT   from the latex of Carica candamarcensis Hook.";
RL   Biol. Chem. Hoppe-Seyler 374:501-506(1993).
CC   -!- SIMILARITY: Belongs to the peptidase C1 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU10088, ECO:0000255|PROSITE-ProRule:PRU10089,
CC       ECO:0000255|PROSITE-ProRule:PRU10090}.
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DR   AlphaFoldDB; P32955; -.
DR   SMR; P32955; -.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR000169; Pept_cys_AS.
DR   InterPro; IPR000668; Peptidase_C1A_C.
DR   Pfam; PF00112; Peptidase_C1; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hydrolase; Protease; Thiol protease.
FT   CHAIN           1..>43
FT                   /note="Cysteine proteinase 2"
FT                   /id="PRO_0000050565"
FT   ACT_SITE        25
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10088,
FT                   ECO:0000255|PROSITE-ProRule:PRU10089, ECO:0000255|PROSITE-
FT                   ProRule:PRU10090"
FT   NON_TER         43
SQ   SEQUENCE   43 AA;  4568 MW;  1777ACB74BC5F34B CRC64;
     YPGSVDWRQK GAVTPVKDQN PCGSCWAFST VATVEGINKI VTG