ID   CYST_SYNE7              Reviewed;         278 AA.
AC   P27367; Q31MK7;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Sulfate transport system permease protein CysT;
GN   Name=cysT; OrderedLocusNames=Synpcc7942_1682;
OS   Synechococcus elongatus (strain PCC 7942 / FACHB-805) (Anacystis nidulans
OS   R2).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=1140;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1708375; DOI=10.1128/jb.173.9.2739-2750.1991;
RA   Laudenbach D.E., Grossman A.R.;
RT   "Characterization and mutagenesis of sulfur-regulated genes in a
RT   cyanobacterium: evidence for function in sulfate transport.";
RL   J. Bacteriol. 173:2739-2750(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7942 / FACHB-805;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Synechococcus elongatus PCC 7942.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1)
CC       involved in sulfate/thiosulfate import. Probably responsible for the
CC       translocation of the substrate across the membrane (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (CysA),
CC       two transmembrane proteins (CysT and CysW) and a solute-binding protein
CC       (CysP). {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- INDUCTION: By sulfur deprivation.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. CysTW subfamily. {ECO:0000305}.
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DR   EMBL; M65247; AAA73044.1; -; Genomic_DNA.
DR   EMBL; CP000100; ABB57712.1; -; Genomic_DNA.
DR   RefSeq; WP_011378140.1; NC_007604.1.
DR   AlphaFoldDB; P27367; -.
DR   SMR; P27367; -.
DR   STRING; 1140.Synpcc7942_1682; -.
DR   PRIDE; P27367; -.
DR   EnsemblBacteria; ABB57712; ABB57712; Synpcc7942_1682.
DR   KEGG; syf:Synpcc7942_1682; -.
DR   eggNOG; COG0555; Bacteria.
DR   HOGENOM; CLU_016047_14_0_3; -.
DR   OMA; VFISGNM; -.
DR   OrthoDB; 1584669at2; -.
DR   BioCyc; SYNEL:SYNPCC7942_1682-MON; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015419; F:ABC-type sulfate transporter activity; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR011865; CysT_permease.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR005667; Sulph_transpt2.
DR   PANTHER; PTHR30406; PTHR30406; 1.
DR   PANTHER; PTHR30406:SF8; PTHR30406:SF8; 1.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   TIGRFAMs; TIGR00969; 3a0106s02; 1.
DR   TIGRFAMs; TIGR02139; permease_CysT; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   2: Evidence at transcript level;
KW   Cell inner membrane; Cell membrane; Membrane; Stress response;
KW   Sulfate transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..278
FT                   /note="Sulfate transport system permease protein CysT"
FT                   /id="PRO_0000059991"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        188..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          63..266
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   278 AA;  30438 MW;  C2FDCF11F7928034 CRC64;
     MSLRLPSLSF TWLTRLSWSW RFTWVYLTLI LFIPIIALFL KSASLPLGRI WELATQPVAV
     AAYEVTFGLS LAAAALNGVF GVIIAWVLTR YDFPGKKLFD SFIDLPFALP TAVAGLTLAT
     VYSDKGWIGQ FIAPFGVQIA FTRWGVLLAM VFISLPFVVR TVEPLLLELE VEAEEAAASL
     GASPSETFWR VILPPILPGV LAGVAQGFSR AVGEFGSVVI ISGNLPFDDL IAPVLIFERL
     EQYDYAGATV IGSVLLLFSL VILFVINALQ NWSSRYNG