CYST_SYNY3
ID CYST_SYNY3 Reviewed; 286 AA.
AC Q01895;
DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 25-MAY-2022, entry version 137.
DE RecName: Full=Sulfate transport system permease protein CysT;
GN Name=cysT; OrderedLocusNames=slr1453;
OS Synechocystis sp. (strain PCC 6803 / Kazusa).
OC Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC unclassified Synechocystis.
OX NCBI_TaxID=1111708;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6803 / Kazusa;
RX PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence analysis of the genome of the unicellular cyanobacterium
RT Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT genome and assignment of potential protein-coding regions.";
RL DNA Res. 3:109-136(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-235.
RX PubMed=8425067; DOI=10.1007/bf00019958;
RA Kohn C., Schumann J.;
RT "Nucleotide sequence and homology comparison of two genes of the sulfate
RT transport operon from the cyanobacterium Synechocystis sp. PCC 6803.";
RL Plant Mol. Biol. 21:409-412(1993).
CC -!- FUNCTION: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1)
CC involved in sulfate/thiosulfate import. Probably responsible for the
CC translocation of the substrate across the membrane (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (CysA),
CC two transmembrane proteins (CysT and CysW) and a solute-binding protein
CC (CysP). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- INDUCTION: By sulfur deprivation.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. CysTW subfamily. {ECO:0000305}.
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DR EMBL; BA000022; BAA18653.1; -; Genomic_DNA.
DR EMBL; X67911; CAA48111.1; -; Genomic_DNA.
DR PIR; S76741; S76741.
DR AlphaFoldDB; Q01895; -.
DR SMR; Q01895; -.
DR STRING; 1148.1653742; -.
DR PaxDb; Q01895; -.
DR EnsemblBacteria; BAA18653; BAA18653; BAA18653.
DR KEGG; syn:slr1453; -.
DR eggNOG; COG0555; Bacteria.
DR InParanoid; Q01895; -.
DR OMA; VFISGNM; -.
DR PhylomeDB; Q01895; -.
DR Proteomes; UP000001425; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015419; F:ABC-type sulfate transporter activity; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR011865; CysT_permease.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR005667; Sulph_transpt2.
DR PANTHER; PTHR30406; PTHR30406; 1.
DR PANTHER; PTHR30406:SF8; PTHR30406:SF8; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR TIGRFAMs; TIGR00969; 3a0106s02; 1.
DR TIGRFAMs; TIGR02139; permease_CysT; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 2: Evidence at transcript level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Stress response; Sulfate transport; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..286
FT /note="Sulfate transport system permease protein CysT"
FT /id="PRO_0000059992"
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 108..128
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 195..215
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 257..276
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 70..273
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 286 AA; 31351 MW; 3C0A1E01F042C587 CRC64;
MTTNLPFSSP SKQLNRFSFW QSISIPWVVT IIYLLLILVL PIAALLVKSA SLGLEGFWQI
ATTPIAISTY NVTFITALAA GLVNGVMGTL VAWVLVRCQF PGKKIVDAMV DLPFALPTSV
AGLVLATLYS QTGWVGRFFA PFGIQIAFSR LGVFVAMVFI SLPFIVRTLQ PVLQELEEEA
EEAAWSLGAT EFQTFWRVIF PPLIPPILTG IALGFSRAVG EYGSVVLIAS NIPFKDLIAP
VLVFERLEQY DYPAATVIGA VLLSVSLILL LIINLLQQWG RRYAND
