ID   CYSW_SYNE7              Reviewed;         286 AA.
AC   P27370; Q31MK4;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Sulfate transport system permease protein CysW;
GN   Name=cysW; OrderedLocusNames=Synpcc7942_1685;
OS   Synechococcus elongatus (strain PCC 7942 / FACHB-805) (Anacystis nidulans
OS   R2).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=1140;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1708375; DOI=10.1128/jb.173.9.2739-2750.1991;
RA   Laudenbach D.E., Grossman A.R.;
RT   "Characterization and mutagenesis of sulfur-regulated genes in a
RT   cyanobacterium: evidence for function in sulfate transport.";
RL   J. Bacteriol. 173:2739-2750(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7942 / FACHB-805;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Synechococcus elongatus PCC 7942.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1)
CC       involved in sulfate/thiosulfate import. Probably responsible for the
CC       translocation of the substrate across the membrane (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (CysA),
CC       two transmembrane proteins (CysT and CysW) and a solute-binding protein
CC       (CysP). {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- INDUCTION: By sulfur deprivation.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. CysTW subfamily. {ECO:0000305}.
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DR   EMBL; M65247; AAA73047.1; -; Genomic_DNA.
DR   EMBL; CP000100; ABB57715.1; -; Genomic_DNA.
DR   RefSeq; WP_011244715.1; NC_007604.1.
DR   AlphaFoldDB; P27370; -.
DR   SMR; P27370; -.
DR   STRING; 1140.Synpcc7942_1685; -.
DR   PRIDE; P27370; -.
DR   EnsemblBacteria; ABB57715; ABB57715; Synpcc7942_1685.
DR   KEGG; syf:Synpcc7942_1685; -.
DR   eggNOG; COG4208; Bacteria.
DR   HOGENOM; CLU_016047_14_0_3; -.
DR   OMA; NEYNFVA; -.
DR   OrthoDB; 1110665at2; -.
DR   BioCyc; SYNEL:SYNPCC7942_1685-MON; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015419; F:ABC-type sulfate transporter activity; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR011866; CysW_permease.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR005667; Sulph_transpt2.
DR   PANTHER; PTHR30406; PTHR30406; 1.
DR   PANTHER; PTHR30406:SF1; PTHR30406:SF1; 1.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   TIGRFAMs; TIGR00969; 3a0106s02; 1.
DR   TIGRFAMs; TIGR02140; permease_CysW; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   2: Evidence at transcript level;
KW   Cell inner membrane; Cell membrane; Membrane; Stress response;
KW   Sulfate transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..286
FT                   /note="Sulfate transport system permease protein CysW"
FT                   /id="PRO_0000059999"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          69..272
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   286 AA;  30671 MW;  A0BEDC2A1915A64A CRC64;
     MVAFVKARRQ IAGVKESKSL LPLALIGISL LYVGLIIIIP AANVAVQAFS EGLSGFIKNL
     GDRNLQEAIR LTLLMGVISV PLNTLFGLAA AFAIARKQFP GKSLLLSVID LPFSISPVVA
     GLMIVLLYGR NGWLGPLLES NDIKIIFAWP GMALATIFVS MPFVAREVIP NLEEIGTDAE
     EAASTLGANG WQTFWRVTLP SIKWSMLYGV VLTTARALGE FGAVSVVSGS ITGKTQTLPL
     FVEEAYKQYQ TTLSYTAALL LGGISLVTLV LKALLEARTG RQSRIH