CYSZ_MANHA
ID CYSZ_MANHA Reviewed; 86 AA.
AC P72205;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Sulfate transporter CysZ {ECO:0000250|UniProtKB:P0A6J3};
DE Flags: Fragment;
GN Name=cysZ;
OS Mannheimia haemolytica (Pasteurella haemolytica).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Mannheimia.
OX NCBI_TaxID=75985;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Serotype A1 / ATCC 43270 / BCRC 13948;
RA Graham M.R., Lo R.Y.C.;
RL Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: High affinity, high specificity proton-dependent sulfate
CC transporter, which mediates sulfate uptake. Provides the sulfur source
CC for the cysteine synthesis pathway. {ECO:0000250|UniProtKB:P0A6J3}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000250|UniProtKB:P0A6J3}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the CysZ family. {ECO:0000305}.
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DR EMBL; U62565; AAB09531.1; -; Genomic_DNA.
DR AlphaFoldDB; P72205; -.
DR SMR; P72205; -.
DR STRING; 75985.WC39_03490; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0008272; P:sulfate transport; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis; Cell inner membrane; Cell membrane;
KW Cysteine biosynthesis; Membrane; Sulfate transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN <1..86
FT /note="Sulfate transporter CysZ"
FT /id="PRO_0000204342"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 64..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
SQ SEQUENCE 86 AA; 9602 MW; 6EBFAD1E9AE7F7FC CRC64;
LNFTFGALVS LFTMIPFVNL VVMPVAVCGA TALWVKEYRN FFLNNQTGEF SKADYTFTKV
NSTSLSTETR TGEVSPNVRN GDIRKQ