CYT10_ORYSJ
ID CYT10_ORYSJ Reviewed; 151 AA.
AC P0C579; B7E949; Q0JDZ3; Q7XKS0;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Cysteine proteinase inhibitor 10;
DE AltName: Full=Oryzacystatin X;
DE Short=OC-X;
DE AltName: Full=Oryzacystatin-10;
DE Flags: Precursor;
GN OrderedLocusNames=Os04g0350100, LOC_Os04g28250; ORFNames=OSJNBa0038P21.11;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP GENE FAMILY.
RX PubMed=15887031; DOI=10.1007/s00438-005-1147-4;
RA Martinez M., Abraham Z., Carbonero P., Diaz I.;
RT "Comparative phylogenetic analysis of cystatin gene families from
RT arabidopsis, rice and barley.";
RL Mol. Genet. Genomics 273:423-432(2005).
CC -!- FUNCTION: Specific inhibitor of cysteine proteinases. Probably involved
CC in the regulation of endogenous processes and in defense against pests
CC and pathogens (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the cystatin family. Phytocystatin subfamily.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL731588; CAE05518.1; -; Genomic_DNA.
DR EMBL; AP008210; BAF14444.1; -; Genomic_DNA.
DR EMBL; AP014960; BAS88722.1; -; Genomic_DNA.
DR EMBL; AK063869; BAG88896.1; -; mRNA.
DR EMBL; AK102139; BAG95408.1; -; mRNA.
DR RefSeq; XP_015635666.1; XM_015780180.1.
DR AlphaFoldDB; P0C579; -.
DR SMR; P0C579; -.
DR STRING; 4530.OS04T0350100-01; -.
DR MEROPS; I25.057; -.
DR PaxDb; P0C579; -.
DR PRIDE; P0C579; -.
DR EnsemblPlants; Os04t0350100-01; Os04t0350100-01; Os04g0350100.
DR GeneID; 4335551; -.
DR Gramene; Os04t0350100-01; Os04t0350100-01; Os04g0350100.
DR KEGG; osa:4335551; -.
DR eggNOG; ENOG502S4YZ; Eukaryota.
DR HOGENOM; CLU_113093_0_1_1; -.
DR InParanoid; P0C579; -.
DR OMA; AEIRHPQ; -.
DR OrthoDB; 1565344at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR Genevisible; P0C579; OS.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR CDD; cd00042; CY; 1.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR046350; Cystatin_sf.
DR Pfam; PF16845; SQAPI; 1.
DR SMART; SM00043; CY; 1.
DR SUPFAM; SSF54403; SSF54403; 1.
PE 2: Evidence at transcript level;
KW Plant defense; Protease inhibitor; Reference proteome; Secreted; Signal;
KW Thiol protease inhibitor.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..151
FT /note="Cysteine proteinase inhibitor 10"
FT /id="PRO_0000277507"
FT DOMAIN 40..109
FT /note="Cystatin"
FT MOTIF 96..100
FT /note="Secondary area of contact"
FT /evidence="ECO:0000250"
FT SITE 40
FT /note="Reactive site"
FT /evidence="ECO:0000250"
SQ SEQUENCE 151 AA; 15448 MW; 9AD8A9ED563F9B6E CRC64;
MATSPMLFLV SLLLVLVAAA TGDEASPSNA AAPAAPVLVG GRTEIRDVGS NKAVQSLGRF
AVAEHNRRLR HGGSGGPADP VPVKLAFARV VEAQKQVVSG VAYYLKVAAS ARDPRGGAAA
GGDRVFDAVV VVKAWLKSKE LVSFTPASST K
