ID   CYYR1_DANRE             Reviewed;         158 AA.
AC   Q6NYG4;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Cysteine and tyrosine-rich protein 1;
DE   Flags: Precursor;
GN   Name=cyyr1; ORFNames=zgc:77252;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Embryo;
RA   Frabetti F., Casadei R., Deflorian G., D'Addabbo P., Vitale L., Lenzi L.,
RA   Ortolani M., Canaider S., Facchin F., Strippoli P., Carinci P.,
RA   Zannotti M., Argenton F.;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CYYR1 family. {ECO:0000305}.
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DR   EMBL; AY690837; AAT99905.1; -; mRNA.
DR   EMBL; BC066606; AAH66606.1; -; mRNA.
DR   RefSeq; NP_998047.1; NM_212882.2.
DR   AlphaFoldDB; Q6NYG4; -.
DR   Ensembl; ENSDART00000160564; ENSDARP00000134426; ENSDARG00000103783.
DR   GeneID; 405818; -.
DR   KEGG; dre:405818; -.
DR   CTD; 116159; -.
DR   ZFIN; ZDB-GENE-040426-2356; cyyr1.
DR   GeneTree; ENSGT00940000167257; -.
DR   HOGENOM; CLU_143594_0_0_1; -.
DR   InParanoid; Q6NYG4; -.
DR   OMA; YSYDYEM; -.
DR   OrthoDB; 1592053at2759; -.
DR   PhylomeDB; Q6NYG4; -.
DR   PRO; PR:Q6NYG4; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 1.
DR   Bgee; ENSDARG00000103783; Expressed in somite and 30 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR022640; CYYR1.
DR   PANTHER; PTHR38490; PTHR38490; 1.
DR   Pfam; PF10873; CYYR1; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000255"
FT   CHAIN           32..158
FT                   /note="Cysteine and tyrosine-rich protein 1"
FT                   /id="PRO_0000341301"
FT   TOPO_DOM        32..62
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        84..158
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          119..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   158 AA;  17156 MW;  775652BCE47325C1 CRC64;
     MENPRSASLQ KSWKFVRESL LLCLIAGRGE AQCDGCIEYC CDGVPPFCCS YYAYVGDVLS
     GTAISGIVFG VVFLMGAVAA VFLCVCMCVK NSRGSRVGVF SSTYINTVTQ GYPGPPPPPY
     SYDHEMFPPD LRPPPYTPTV PRSANYSPPP PYPGFSRK