ID   CZCR_BACAN              Reviewed;         288 AA.
AC   Q81VJ1; Q6I4J0; Q6KY92;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 127.
DE   RecName: Full=HTH-type transcriptional regulator CzcR;
GN   Name=czcR; OrderedLocusNames=BA_0208, GBAA_0208, BAS0205;
OS   Bacillus anthracis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames / isolate Porton;
RX   PubMed=12721629; DOI=10.1038/nature01586;
RA   Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T.,
RA   Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R.,
RA   Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M.,
RA   Kolonay J.F., Beanan M.J., Dodson R.J., Brinkac L.M., Gwinn M.L.,
RA   DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C.,
RA   Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y.,
RA   Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M.,
RA   Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E.,
RA   White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M.,
RA   Hanna P.C., Kolstoe A.-B., Fraser C.M.;
RT   "The genome sequence of Bacillus anthracis Ames and comparison to closely
RT   related bacteria.";
RL   Nature 423:81-86(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames ancestor;
RX   PubMed=18952800; DOI=10.1128/jb.01347-08;
RA   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA   Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT   "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL   J. Bacteriol. 191:445-446(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sterne;
RA   Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K.,
RA   Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R.,
RA   Richardson P., Rubin E., Tice H.;
RT   "Complete genome sequence of Bacillus anthracis Sterne.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; AE016879; AAP24255.1; -; Genomic_DNA.
DR   EMBL; AE017334; AAT29292.1; -; Genomic_DNA.
DR   EMBL; AE017225; AAT52541.1; -; Genomic_DNA.
DR   RefSeq; NP_842769.1; NC_003997.3.
DR   RefSeq; WP_000423056.1; NZ_WXXJ01000014.1.
DR   RefSeq; YP_026490.1; NC_005945.1.
DR   AlphaFoldDB; Q81VJ1; -.
DR   SMR; Q81VJ1; -.
DR   STRING; 261594.GBAA_0208; -.
DR   DNASU; 1086828; -.
DR   EnsemblBacteria; AAP24255; AAP24255; BA_0208.
DR   EnsemblBacteria; AAT29292; AAT29292; GBAA_0208.
DR   GeneID; 45020257; -.
DR   KEGG; ban:BA_0208; -.
DR   KEGG; bar:GBAA_0208; -.
DR   KEGG; bat:BAS0205; -.
DR   PATRIC; fig|198094.11.peg.205; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_1_9; -.
DR   OMA; AFERGCT; -.
DR   Proteomes; UP000000427; Chromosome.
DR   Proteomes; UP000000594; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..288
FT                   /note="HTH-type transcriptional regulator CzcR"
FT                   /id="PRO_0000334138"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   288 AA;  32705 MW;  DAD0831AAB06EA14 CRC64;
     MELRDLQIFQ SVADQGSVSS AAKELNYVQS NVTARIKQLE NELKTPLFYR HKRGMTLTAE
     GRKMLVYVNK ILQDVDELKQ VFLDSETPSG ILKIGTVETV STLPTILSSY YKSYPNVDLS
     LQAGLTEELI REVLDHQLDG AFISGPIKHP LIEQYDVSTE KLMLVTQNKT FHIEEFTTTP
     LLVFNQGCGY RSKLERWLKD EGLLPKRIME FNILETLLNS VALGLGITLV PQSAVHHLSK
     AGKVHCHAIP EKYGSISTVF IRRKDSYMTN SMRSFLKTIE EHHHINML