ID   CZCR_BACC1              Reviewed;         288 AA.
AC   Q73EY2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=HTH-type transcriptional regulator CzcR;
GN   Name=czcR; OrderedLocusNames=BCE_0226;
OS   Bacillus cereus (strain ATCC 10987 / NRS 248).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=222523;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10987 / NRS 248;
RX   PubMed=14960714; DOI=10.1093/nar/gkh258;
RA   Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L.,
RA   Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F.,
RA   Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D.;
RT   "The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic
RT   adaptations and a large plasmid related to Bacillus anthracis pXO1.";
RL   Nucleic Acids Res. 32:977-988(2004).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; AE017194; AAS39162.1; -; Genomic_DNA.
DR   RefSeq; WP_000423054.1; NC_003909.8.
DR   AlphaFoldDB; Q73EY2; -.
DR   SMR; Q73EY2; -.
DR   EnsemblBacteria; AAS39162; AAS39162; BCE_0226.
DR   GeneID; 59156581; -.
DR   KEGG; bca:BCE_0226; -.
DR   HOGENOM; CLU_039613_6_1_9; -.
DR   OMA; AFERGCT; -.
DR   Proteomes; UP000002527; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..288
FT                   /note="HTH-type transcriptional regulator CzcR"
FT                   /id="PRO_0000334139"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   288 AA;  32675 MW;  6A81874FEF06E5B9 CRC64;
     MELRDLQIFQ SVADQGSVSS AAKELNYVQS NVTARIKQLE NELKTPLFYR HKRGMTLTAE
     GRKMLVYVNK ILQDVDELKQ VFLDSETPSG ILKIGTVETV STLPTILSSY YKSYPNVDLS
     LQAGLTEELI REVLDHQLDG AFISGPIKHP LIEQYDVSTE KLMLVTQNKA FHIEEFTTTP
     LLVFNQGCGY RSKLERWLKD EGLLPKRIME FNILETILNS VALGLGITLV PQSAVHHLSK
     AGKVHCHAIP EKYGSISTVF IRRKDSYMTN SMRSFLKTIE EHHHINML