ID   CZCR_BACCR              Reviewed;         288 AA.
AC   Q81IX0;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=HTH-type transcriptional regulator CzcR;
GN   Name=czcR; OrderedLocusNames=BC_0224;
OS   Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC
OS   15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=226900;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373
RC   / NCTC 2599 / NRRL B-3711;
RX   PubMed=12721630; DOI=10.1038/nature01582;
RA   Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V.,
RA   Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M.,
RA   Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G.,
RA   Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C.;
RT   "Genome sequence of Bacillus cereus and comparative analysis with Bacillus
RT   anthracis.";
RL   Nature 423:87-91(2003).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; AE016877; AAP07293.1; -; Genomic_DNA.
DR   RefSeq; NP_830092.1; NC_004722.1.
DR   RefSeq; WP_000423031.1; NZ_CP034551.1.
DR   AlphaFoldDB; Q81IX0; -.
DR   SMR; Q81IX0; -.
DR   STRING; 226900.BC_0224; -.
DR   EnsemblBacteria; AAP07293; AAP07293; BC_0224.
DR   GeneID; 67504910; -.
DR   KEGG; bce:BC0224; -.
DR   PATRIC; fig|226900.8.peg.221; -.
DR   HOGENOM; CLU_039613_6_1_9; -.
DR   OMA; AFERGCT; -.
DR   Proteomes; UP000001417; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..288
FT                   /note="HTH-type transcriptional regulator CzcR"
FT                   /id="PRO_0000334140"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   288 AA;  32648 MW;  03304F4EA317F3FC CRC64;
     MELRDLQIFK SVADQGSVSS AAKELNYVQS NVTARIKQLE NELKTPLFYR HKRGMTLTAE
     GRKMLVYVSK ILQDVDELKQ VFLDSETPSG ILKIGTVETV STLPTILSSY YKSYPNVDLS
     LQAGLTEELI REVLDHQLDG AFISGPIKHP LIEQYDVSTE KLMLITQNKA FHIEEFTTTP
     LLVFNQGCGY RSKLERWLKD EGLLPKRIME FNILETILNS VALGLGITLV PQSAVHHLSK
     AGKVHCHAIP EKYGSISTVF IRRKDSYMTN SMRSFLKTIE DHHHINML