ID   CZCR_BACHK              Reviewed;         288 AA.
AC   Q6HPH4;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=HTH-type transcriptional regulator CzcR;
GN   Name=czcR; OrderedLocusNames=BT9727_0191;
OS   Bacillus thuringiensis subsp. konkukian (strain 97-27).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=281309;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=97-27;
RX   PubMed=16621833; DOI=10.1128/jb.188.9.3382-3390.2006;
RA   Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D.,
RA   Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C.,
RA   Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A.,
RA   Hill K.K., Hitchcock P., Jackson P.J., Keim P., Kewalramani A.R.,
RA   Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M.,
RA   Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B.,
RA   Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R.,
RA   Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L.,
RA   Brettin T.S., Gilna P.;
RT   "Pathogenomic sequence analysis of Bacillus cereus and Bacillus
RT   thuringiensis isolates closely related to Bacillus anthracis.";
RL   J. Bacteriol. 188:3382-3390(2006).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; AE017355; AAT60040.1; -; Genomic_DNA.
DR   RefSeq; WP_000423058.1; NC_005957.1.
DR   RefSeq; YP_034546.1; NC_005957.1.
DR   AlphaFoldDB; Q6HPH4; -.
DR   SMR; Q6HPH4; -.
DR   EnsemblBacteria; AAT60040; AAT60040; BT9727_0191.
DR   KEGG; btk:BT9727_0191; -.
DR   PATRIC; fig|281309.8.peg.198; -.
DR   HOGENOM; CLU_039613_6_1_9; -.
DR   OMA; AFERGCT; -.
DR   Proteomes; UP000001301; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..288
FT                   /note="HTH-type transcriptional regulator CzcR"
FT                   /id="PRO_0000334144"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   288 AA;  32705 MW;  6A818B3EEF06E0B8 CRC64;
     MELRDLQIFQ SVADQGSVSS AAKELNYVQS NVTTRIKQLE NELKTPLFYR HKRGMTLTAE
     GRKMLVYVNK ILQDVDELKQ VFLDSETPSG ILKIGTVETV STLPTILSSY YKSYPNVDLS
     LQAGLTEELI REVLDHQLDG AFISGPIKHP LIEQYDVSTE KLMLVTQNKA FHIEEFTTTP
     LLVFNQGCGY RSKLERWLKD EGLLPKRIME FNILETILNS VALGLGITLV PQSAVHHLSK
     AGKVHCHAIP EKYGSISTVF IRRKDSYMTN SMRSFLKTIE EHHHINML