ID   CZIB_RAT                Reviewed;         160 AA.
AC   Q498R7;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=CXXC motif containing zinc binding protein {ECO:0000305};
DE   AltName: Full=UPF0587 protein C1orf123 homolog;
GN   Name=Czib {ECO:0000312|RGD:1559786};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBUNIT: Monomer. {ECO:0000250|UniProtKB:Q9NWV4}.
CC   -!- DOMAIN: The N-terminal and the C-terminal half of the protein have a
CC       very similar 3D-structure, suggesting they arose from duplication.
CC       Requires a bound zinc ion for normal folding and solubility.
CC       {ECO:0000250|UniProtKB:Q9NWV4}.
CC   -!- SIMILARITY: Belongs to the UPF0587 family. {ECO:0000305}.
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DR   EMBL; BC100100; AAI00101.1; -; mRNA.
DR   RefSeq; NP_001029304.1; NM_001034132.1.
DR   AlphaFoldDB; Q498R7; -.
DR   SMR; Q498R7; -.
DR   STRING; 10116.ENSRNOP00000058861; -.
DR   PaxDb; Q498R7; -.
DR   PRIDE; Q498R7; -.
DR   Ensembl; ENSRNOT00000065275; ENSRNOP00000058861; ENSRNOG00000012724.
DR   GeneID; 298384; -.
DR   KEGG; rno:298384; -.
DR   UCSC; RGD:1559786; rat.
DR   CTD; 54987; -.
DR   RGD; 1559786; Czib.
DR   eggNOG; KOG1296; Eukaryota.
DR   GeneTree; ENSGT00390000001523; -.
DR   HOGENOM; CLU_114688_1_0_1; -.
DR   InParanoid; Q498R7; -.
DR   OMA; FFMKCKM; -.
DR   OrthoDB; 1398309at2759; -.
DR   PhylomeDB; Q498R7; -.
DR   PRO; PR:Q498R7; -.
DR   Proteomes; UP000002494; Chromosome 5.
DR   Bgee; ENSRNOG00000012724; Expressed in skeletal muscle tissue and 20 other tissues.
DR   Genevisible; Q498R7; RN.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   InterPro; IPR008584; CXXC_Zn-binding_euk.
DR   PANTHER; PTHR12857; PTHR12857; 1.
DR   Pfam; PF05907; DUF866; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; Phosphoprotein; Reference proteome; Zinc.
FT   CHAIN           1..160
FT                   /note="CXXC motif containing zinc binding protein"
FT                   /id="PRO_0000264153"
FT   BINDING         33
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT   BINDING         36
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT   BINDING         67
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT   BINDING         70
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT   MOD_RES         75
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
SQ   SEQUENCE   160 AA;  18095 MW;  7AC37E2AF7061811 CRC64;
     MGKIALQLKA TLENVTNLRP VGEDFRWYLK MKCGNCGEIS EKWQYIRLMD SVALKGGRGS
     ASMVQKCKLC ARENSIEILS STIKSYNAED NEKFKTIVEF ECRGLEPVDF QPQAGFAAEG
     VESGTVFSDI NLQEKDWTDY DEKTQESVGI FEVTHQFVKC