ID   CZIB_XENLA              Reviewed;         160 AA.
AC   Q3B8G0;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=CXXC motif containing zinc binding protein {ECO:0000305};
DE   AltName: Full=UPF0587 protein C1orf123 homolog;
GN   Name=czib;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- DOMAIN: The N-terminal and the C-terminal half of the protein have a
CC       very similar 3D-structure, suggesting they arose from duplication.
CC       Requires a bound zinc ion for normal folding and solubility.
CC       {ECO:0000250|UniProtKB:Q9NWV4}.
CC   -!- SIMILARITY: Belongs to the UPF0587 family. {ECO:0000305}.
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DR   EMBL; BC106465; AAI06466.1; -; mRNA.
DR   RefSeq; NP_001089748.1; NM_001096279.1.
DR   AlphaFoldDB; Q3B8G0; -.
DR   SMR; Q3B8G0; -.
DR   MaxQB; Q3B8G0; -.
DR   DNASU; 734812; -.
DR   GeneID; 734812; -.
DR   KEGG; xla:734812; -.
DR   CTD; 734812; -.
DR   Xenbase; XB-GENE-5847273; czib.L.
DR   OrthoDB; 1398309at2759; -.
DR   Proteomes; UP000186698; Chromosome 4L.
DR   Bgee; 734812; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   InterPro; IPR008584; CXXC_Zn-binding_euk.
DR   PANTHER; PTHR12857; PTHR12857; 1.
DR   Pfam; PF05907; DUF866; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; Reference proteome; Zinc.
FT   CHAIN           1..160
FT                   /note="CXXC motif containing zinc binding protein"
FT                   /id="PRO_0000264154"
FT   BINDING         33
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT   BINDING         36
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT   BINDING         67
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT   BINDING         70
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NWV4"
SQ   SEQUENCE   160 AA;  18221 MW;  3D3A2E1A7026D8BF CRC64;
     MVKFALQFKA SLENLTQLRP HGEDFRWFLK LKCGNCGEVS DKWQYITLMD SVPLKGGRGS
     ASMVQRCKLC SRENSIDILA ASLHPYNAED SETFKTIVEF ECRGLEPIDF QPQAGFAAEG
     AETGTPFHEI NLQEKDWTDY DEKAKESVGI YEVEHRFTKC