C_HENDH
ID C_HENDH Reviewed; 166 AA.
AC O55779;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 56.
DE RecName: Full=Protein C;
GN Name=P/V/C;
OS Hendra virus (isolate Horse/Autralia/Hendra/1994).
OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae;
OC Henipavirus.
OX NCBI_TaxID=928303;
OH NCBI_TaxID=9796; Equus caballus (Horse).
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9402; Pteropus alecto (Black flying fox).
OH NCBI_TaxID=9403; Pteropus poliocephalus (Grey-headed flying fox).
OH NCBI_TaxID=94117; Pteropus scapulatus (Little red flying fox).
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=9445051; DOI=10.1128/jvi.72.2.1482-1490.1998;
RA Wang L.-F., Michalski W.P., Yu M., Pritchard L.I., Crameri G., Shiell B.,
RA Eaton B.T.;
RT "A novel P/V/C gene in a new member of the Paramyxoviridae family, which
RT causes lethal infection in humans, horses, and other animals.";
RL J. Virol. 72:1482-1490(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=11024125; DOI=10.1128/jvi.74.21.9972-9979.2000;
RA Wang L.-F., Yu M., Hansson E., Pritchard L.I., Shiell B., Michalski W.P.,
RA Eaton B.T.;
RT "The exceptionally large genome of Hendra virus: support for creation of a
RT new genus within the family Paramyxoviridae.";
RL J. Virol. 74:9972-9979(2000).
CC -!- FUNCTION: May counteract the cellular interferon antiviral system.
CC -!- MISCELLANEOUS: The P/V/C gene has two overlapping open reading frames.
CC One encodes the P/V/W proteins and the other the C protein.
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DR EMBL; AF010304; AAC04242.1; -; mRNA.
DR EMBL; AF017149; AAC83190.1; -; Genomic_RNA.
DR PIR; T08208; T08208.
DR RefSeq; NP_047109.1; NC_001906.3.
DR IntAct; O55779; 9.
DR GeneID; 1446469; -.
DR Proteomes; UP000008771; Genome.
DR InterPro; IPR031812; C_Hendra.
DR Pfam; PF16821; C_Hendra; 1.
PE 2: Evidence at transcript level;
KW Interferon antiviral system evasion; Reference proteome.
FT CHAIN 1..166
FT /note="Protein C"
FT /id="PRO_0000236018"
FT REGION 17..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 166 AA; 19646 MW; 0213AAA3B704DD02 CRC64;
MMASILLTLF RRTKKKYKRH TDDQASNNQV PKTGQEHGRT SCRAPVENMN RLRGECLRMM
EVLKEEMWRI YPVLLPQMEL LDKECQTPEL GQKTQMTYNW TQWLQTLYTM IMEENVPDMD
LLQALREGGV ITCQEHTMGM YVLYLIQRCC PMLPKLQFLK KLGKLI