C_NIPAV
ID C_NIPAV Reviewed; 166 AA.
AC Q997F1;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 50.
DE RecName: Full=Protein C;
GN Name=P/V/C;
OS Nipah virus.
OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae;
OC Henipavirus.
OX NCBI_TaxID=121791;
OH NCBI_TaxID=58060; Cynopterus brachyotis (Lesser short-nosed fruit bat) (Pachysoma brachyotis).
OH NCBI_TaxID=58065; Eonycteris spelaea (Lesser dawn bat) (Macroglossus spelaeus).
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9405; Pteropus hypomelanus (Island flying fox) (Variable flying fox).
OH NCBI_TaxID=132908; Pteropus vampyrus (Large flying fox).
OH NCBI_TaxID=153297; Scotophilus kuhlii (Lesser asiatic yellow bat).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=10827955; DOI=10.1126/science.288.5470.1432;
RA Chua K.B., Bellini W.J., Rota P.A., Harcourt B.H., Tamin A., Lam S.K.,
RA Ksiazek T.G., Rollin P.E., Zaki S.R., Shieh W., Goldsmith C.S.,
RA Gubler D.J., Roehrig J.T., Eaton B., Gould A.R., Olson J., Field H.,
RA Daniels P., Ling A.E., Peters C.J., Anderson L.J., Mahy B.W.;
RT "Nipah virus: a recently emergent deadly paramyxovirus.";
RL Science 288:1432-1435(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=Isolate UMMC1, and Isolate UMMC2;
RX PubMed=11514724; DOI=10.1099/0022-1317-82-9-2151;
RA Chan Y.P., Chua K.B., Koh C.L., Lim M.E., Lam S.K.;
RT "Complete nucleotide sequences of Nipah virus isolates from Malaysia.";
RL J. Gen. Virol. 82:2151-2155(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=Isolate Malaysian flying-fox;
RX PubMed=11880045; DOI=10.1016/s1286-4579(01)01522-2;
RA Chua K.B., Koh C.L., Hooi P.S., Wee K.F., Khong J.H., Chua B.H., Chan Y.P.,
RA Lim M.E., Lam S.K.;
RT "Isolation of Nipah virus from Malaysian island flying-foxes.";
RL Microbes Infect. 4:145-151(2002).
CC -!- FUNCTION: May counteract the cellular interferon antiviral system.
CC -!- MISCELLANEOUS: The P/V/C gene has two overlapping open reading frames.
CC One encodes the P/V/W proteins and the other the C protein.
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DR EMBL; AF212302; AAK29086.1; -; Genomic_RNA.
DR EMBL; AY029768; AAK50550.1; -; Genomic_RNA.
DR EMBL; AY029767; AAK50542.1; -; Genomic_RNA.
DR EMBL; AF376747; AAM13403.1; -; Genomic_RNA.
DR RefSeq; NP_112024.1; NC_002728.1.
DR IntAct; Q997F1; 17.
DR MINT; Q997F1; -.
DR PRIDE; Q997F1; -.
DR GeneID; 920952; -.
DR Proteomes; UP000002330; Genome.
DR Proteomes; UP000007527; Genome.
DR Proteomes; UP000008676; Genome.
DR InterPro; IPR031812; C_Hendra.
DR Pfam; PF16821; C_Hendra; 1.
PE 4: Predicted;
KW Interferon antiviral system evasion.
FT CHAIN 1..166
FT /note="Protein C"
FT /id="PRO_0000236019"
SQ SEQUENCE 166 AA; 19736 MW; 6D04F7F36893011D CRC64;
MMASILLTLF RRTKKKYRRH TDDQVFNNPA SKIKQKPGKI FCSAPVENLN KLRGECLRMM
EMLKEETWRI YPVLLPQMEL LERECRTPVT GQKVQMTYNW TQWLQTLYTM IMEENVPDMD
LLQALREGGV ITHQEQTMGM YVLYLMQRCC PMLPKLQFLK KIGKLI