ID   C_PI3B                  Reviewed;         201 AA.
AC   P06164;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   23-FEB-2022, entry version 61.
DE   RecName: Full=Protein C;
GN   Name=P/V/C;
OS   Bovine parainfluenza 3 virus (BPIV-3).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae;
OC   Respirovirus.
OX   NCBI_TaxID=11215;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=910N;
RX   PubMed=3031614; DOI=10.1093/nar/15.7.2927;
RA   Sakai Y., Suzu S., Shioda T., Shibuta H.;
RT   "Nucleotide sequence of the bovine parainfluenza 3 virus genome: its 3' end
RT   and the genes of NP, P, C and M proteins.";
RL   Nucleic Acids Res. 15:2927-2944(1987).
CC   -!- INTERACTION:
CC       P06164; Q60680: Chuk; Xeno; NbExp=2; IntAct=EBI-8848117, EBI-646245;
CC   -!- SIMILARITY: Belongs to the respirovirus protein C family.
CC       {ECO:0000305}.
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DR   EMBL; Y00114; CAA68295.1; -; Genomic_RNA.
DR   EMBL; D84095; BAA12215.1; -; Genomic_RNA.
DR   SMR; P06164; -.
DR   IntAct; P06164; 1.
DR   MINT; P06164; -.
DR   Proteomes; UP000133413; Genome.
DR   GO; GO:0039563; P:suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity; ISS:UniProtKB.
DR   GO; GO:0039564; P:suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity; IEA:UniProtKB-KW.
DR   GO; GO:0039502; P:suppression by virus of host type I interferon-mediated signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR002608; Paramyxo_C.
DR   Pfam; PF01692; Paramyxo_C; 1.
PE   1: Evidence at protein level;
KW   Host-virus interaction; Inhibition of host innate immune response by virus;
KW   Inhibition of host interferon signaling pathway by virus;
KW   Inhibition of host STAT1 by virus; Inhibition of host STAT2 by virus;
KW   Viral immunoevasion.
FT   CHAIN           1..201
FT                   /note="Protein C"
FT                   /id="PRO_0000142802"
FT   REGION          15..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..70
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   201 AA;  23509 MW;  5539A9EEC6BBF550 CRC64;
     MLKTIKSWIL GKRDQETSHL TSHRPSTSLN SYSAPTPKRT RQTAMKSTQG TRDSARQSTN
     LNPKQQKQAK KIVDQLTKID SLGHHTNVPQ RQRIEMLIRR LYREEIGEEA AQIVELRLWS
     LEESPEAAQI LTMEPKSRKV LITMKLERWI RTLLRGKCDN LKMFQSRYQE VMPFLQQNKM
     ETVMMEEAWN LSVHLIQDIP A