ID   D39U1_BOVIN             Reviewed;         294 AA.
AC   Q17QH8;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Epimerase family protein SDR39U1;
DE            EC=1.1.1.-;
DE   AltName: Full=Short-chain dehydrogenase/reductase family 39U member 1 {ECO:0000250|UniProtKB:Q9NRG7};
GN   Name=SDR39U1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal pons;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative NADP-dependent oxidoreductase. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. SDR39U1 subfamily. {ECO:0000305}.
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DR   EMBL; BC118349; AAI18350.1; -; mRNA.
DR   RefSeq; NP_001069280.1; NM_001075812.2.
DR   AlphaFoldDB; Q17QH8; -.
DR   SMR; Q17QH8; -.
DR   STRING; 9913.ENSBTAP00000044527; -.
DR   PaxDb; Q17QH8; -.
DR   GeneID; 520897; -.
DR   KEGG; bta:520897; -.
DR   CTD; 56948; -.
DR   eggNOG; KOG3019; Eukaryota.
DR   InParanoid; Q17QH8; -.
DR   OrthoDB; 1498565at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR013549; DUF1731.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR010099; SDR39U1.
DR   Pfam; PF08338; DUF1731; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR01777; yfcH; 1.
PE   2: Evidence at transcript level;
KW   NADP; Oxidoreductase; Reference proteome.
FT   CHAIN           1..294
FT                   /note="Epimerase family protein SDR39U1"
FT                   /id="PRO_0000279747"
FT   BINDING         31..32
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NRG7"
FT   BINDING         58..59
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NRG7"
FT   BINDING         77
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NRG7"
FT   BINDING         82
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NRG7"
FT   BINDING         160
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NRG7"
SQ   SEQUENCE   294 AA;  31334 MW;  F6695C6DA14B225F CRC64;
     MRVLVGGGTG FIGTALTQLL KARGHEVTLI SRKPGPDRIT WDDLTTSGLP RCDAAVNLAG
     ENILNPLRRW NAAFQKEVLS SRLETTQTLA RAIAKAPQPP QAWVLVTGVA YYQPSLTAEY
     DEDSPGGDFD FFSNLVTKWE AAARLPGDST RQVVVRSGVV LGRGGGAIGH MLLPFRLGLG
     GPIGSGHQFF PWIHIRDLAG ILAHALETSH VQGILNGVAP ASSTTNAEFA RALGTALGRP
     AFIPLPSAVV QAVFGRERAV MLLEGQKVVP RRTLAAGYRY SFPELGAALK EVIA