ID   D3_VACCA                Reviewed;         233 AA.
AC   O57210;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   29-SEP-2021, entry version 48.
DE   RecName: Full=Core protein D3;
DE   AltName: Full=27 kDa virion core protein;
GN   OrderedLocusNames=MVA100R, ACAM3000_MVA_100; ORFNames=D3R;
OS   Vaccinia virus (strain Ankara) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=126794;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9601507; DOI=10.1006/viro.1998.9123;
RA   Antoine G., Scheiflinger F., Dorner F., Falkner F.G.;
RT   "The complete genomic sequence of the modified vaccinia Ankara strain:
RT   comparison with other orthopoxviruses.";
RL   Virology 244:365-396(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate Acambis 3000;
RA   Esposito J.J., Frace M., Sammons S.A., Olsen-Rasmussen M.S., Osborne J.,
RA   Khristova M., Wohlhueter R.M.;
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Late protein which is part of a large complex required for
CC       early virion morphogenesis. This complex participates in the formation
CC       of virosomes and the incorporation of virosomal contents into nascent
CC       immature virions (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Part of a complex composed of A30, G7, F10 kinase, A15, D2,
CC       D3, and J1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Note=Localizes to the
CC       virion core. {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae D3 family. {ECO:0000305}.
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DR   EMBL; U94848; AAB96512.1; -; Genomic_DNA.
DR   EMBL; AY603355; AAT10498.1; -; Genomic_DNA.
DR   PIR; T37376; T37376.
DR   Proteomes; UP000159908; Genome.
DR   Proteomes; UP000172909; Genome.
DR   InterPro; IPR007660; Pox_D3.
DR   Pfam; PF04580; Pox_D3; 1.
PE   2: Evidence at transcript level;
KW   Late protein; Virion.
FT   CHAIN           1..233
FT                   /note="Core protein D3"
FT                   /id="PRO_0000099427"
SQ   SEQUENCE   233 AA;  27553 MW;  6CA7273F6CCC3026 CRC64;
     MDIFIVKDNK YPKVDNDDNE VFILLGNHND FIRSKLTKLK EHVFFSEYIV TPDTYGSLCV
     ELNGSSFQHG GRYIEVEEFI DAGRQVRWCS TSNHISEDMH TDKFVIYDIY TFDSFKNKRL
     VFVQVPPSLG DDSYLTNPLL SPYYRNSVAR QMVNDMIFNQ DSFLKYLLEH LIRSHYRVSK
     HITIVRYKDT EELNLTRICY NRDKFKAFVF AWFNGVSENE KVLDTYKKVS NLI