ID   D3_VACCC                Reviewed;         237 AA.
AC   P21009;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   29-SEP-2021, entry version 59.
DE   RecName: Full=Core protein D3;
DE   AltName: Full=27 kDa virion core protein;
GN   ORFNames=D3R;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   COMPLETE GENOME.
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- FUNCTION: Late protein which is part of a large complex required for
CC       early virion morphogenesis. This complex participates in the formation
CC       of virosomes and the incorporation of virosomal contents into nascent
CC       immature virions (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Part of a complex composed of A30, G7, F10 kinase, A15, D2,
CC       D3, and J1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Note=Localizes to the
CC       virion core. {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae D3 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M35027; AAA48099.1; -; Genomic_DNA.
DR   PIR; B42515; QQVZCG.
DR   Proteomes; UP000008269; Genome.
DR   InterPro; IPR007660; Pox_D3.
DR   Pfam; PF04580; Pox_D3; 1.
PE   2: Evidence at transcript level;
KW   Late protein; Reference proteome; Virion.
FT   CHAIN           1..237
FT                   /note="Core protein D3"
FT                   /id="PRO_0000099428"
SQ   SEQUENCE   237 AA;  27974 MW;  3CBF3C7053704722 CRC64;
     MDIFIVKDNK YPKVDNDDNE VFILLGNHND FIRLKLTKLK EHVFFSEYIV TPDTYGSLCV
     ELNGSSFQHG GRYIEVEEFI DAGRQVRWCS TSNHISEDIP EDIHTDKFVI YDIYTFDAFK
     NKRLVFVQVP PSLGDDSHLT NPLLSPYYRN SVARQMVNDM IFNQDSFLKY LLEHLIRSHY
     RVSKHITIVR YKDTEELNLT RICYNRDKFK AFVFAWFNGV SENEKVLDTY KKVSNLI