ID   D9043_DICDI             Reviewed;         588 AA.
AC   P0DPA1; Q54J59;
DT   25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2017, sequence version 1.
DT   25-MAY-2022, entry version 20.
DE   RecName: Full=WD repeat-containing protein DDB_G0349043;
GN   ORFNames=DDB_G0349043;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P0DPA1; -.
DR   SMR; P0DPA1; -.
DR   STRING; 44689.DDB0219330; -.
DR   eggNOG; KOG0293; Eukaryota.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0034657; C:GID complex; IBA:GO_Central.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR024977; Apc4_WD40_dom.
DR   InterPro; IPR006595; CTLH_C.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR006594; LisH.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   Pfam; PF00400; WD40; 3.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00668; CTLH; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50897; CTLH; 1.
DR   PROSITE; PS50896; LISH; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..588
FT                   /note="WD repeat-containing protein DDB_G0349043"
FT                   /id="PRO_0000442006"
FT   DOMAIN          40..72
FT                   /note="LisH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00126"
FT   DOMAIN          73..129
FT                   /note="CTLH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00058"
FT   REPEAT          244..283
FT                   /note="WD 1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          294..333
FT                   /note="WD 2"
FT                   /evidence="ECO:0000255"
FT   REPEAT          336..375
FT                   /note="WD 3"
FT                   /evidence="ECO:0000255"
FT   REPEAT          413..452
FT                   /note="WD 4"
FT                   /evidence="ECO:0000255"
FT   REPEAT          455..494
FT                   /note="WD 5"
FT                   /evidence="ECO:0000255"
FT   REPEAT          499..539
FT                   /note="WD 6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          542..582
FT                   /note="WD 7"
FT                   /evidence="ECO:0000255"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          376..403
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..32
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   588 AA;  67627 MW;  4D494F4CEED4BA59 CRC64;
     MPLDNKVQLN ENGKEVNNNN NNDEDLKIQD NHNNKEPFFN RSELVRLLIQ SLNSLGYDKS
     AEFLEKDSGI SLQSKEINQF SECVVSGDWN KVEELLPFLK LNEFDTNNVK FLVYSQKFLE
     YLENHKIKEA LECLRLEITP YTKDTSRLQV LTSLIMTSNS SETKKQIKQR SSRVNLLDDI
     RKYVNPNIML PENRLEQLIK QSIQYQMGKC LYHNTSEQFI NLFKDHTCDK SQMPLDVLFT
     LKDKHRDEIW FITFSHDGQR LASSSKDNTI IIWDMSTIYL DQPTEPKVMF ILLGHTKEVS
     HLSWSPNDKY LLSASNDSTV KLWNTNDGTL LKTFTKHSDA VTCCGWHPDN KRFVSGGNDK
     NIYLWSIENL DLTNSNNNNN NHNNNNSNIN GNSINGSNNN GNNNNNISPI KSWACARVND
     LSIHKDGKQL IIICQEKKLR IYDLENEKTP EVVLMETDAI TSMELSNDCN FALVNTSNQE
     IHLWDLEKQI IVQKYRGHKQ GRFVIRSCFG GVDQAFVLSG SEDSTIYIWH RSSGILLETL
     SRHSGTVNTV CWSPCNPFIF CSASDDQTIK VWSRSNNHNS FINNLTNK