DAAF8_BOVIN
ID DAAF8_BOVIN Reviewed; 361 AA.
AC Q2KIS6;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 07-MAR-2006, sequence version 1.
DT 25-MAY-2022, entry version 47.
DE RecName: Full=Dynein axonemal assembly factor 8 {ECO:0000305};
DE AltName: Full=Dynein axonemal-associated protein 1 {ECO:0000305};
DE AltName: Full=Uncharacterized protein C16orf71 homolog;
GN Name=DNAAF8; Synonyms=DAAP1 {ECO:0000250|UniProtKB:Q8IYS4};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Testis;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: In cyliated cells, dynein axonemal particle-specific protein
CC required for deployment of ODA to the axoneme. Interacts with outer
CC dynein arm (ODA) subunits. {ECO:0000250|UniProtKB:A0A1L8EYB2}.
CC -!- SUBCELLULAR LOCATION: Dynein axonemal particle
CC {ECO:0000250|UniProtKB:Q8IYS4}.
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DR EMBL; BC112526; AAI12527.1; -; mRNA.
DR RefSeq; NP_001040086.1; NM_001046621.2.
DR AlphaFoldDB; Q2KIS6; -.
DR STRING; 9913.ENSBTAP00000008661; -.
DR PaxDb; Q2KIS6; -.
DR PRIDE; Q2KIS6; -.
DR GeneID; 618674; -.
DR KEGG; bta:618674; -.
DR CTD; 146562; -.
DR eggNOG; ENOG502SAQ4; Eukaryota.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0120293; C:dynein axonemal particle; ISS:UniProtKB.
DR GO; GO:0070840; F:dynein complex binding; ISS:UniProtKB.
DR GO; GO:0036158; P:outer dynein arm assembly; ISS:UniProtKB.
DR InterPro; IPR031531; DNAAF8.
DR PANTHER; PTHR35977; PTHR35977; 1.
DR Pfam; PF15773; DUF4701; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Phosphoprotein; Reference proteome.
FT CHAIN 1..361
FT /note="Dynein axonemal assembly factor 8"
FT /id="PRO_0000294344"
FT REGION 65..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 142
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5XIK6"
FT MOD_RES 144
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5XIK6"
SQ SEQUENCE 361 AA; 38831 MW; 8A2786574A7A5A9A CRC64;
MASPDEDGRP SLPNPWDAIL EAVKHQLPSL DSDSSASDCE DEELFIFQRN QTVLIPDLSE
ELADDPAGAW VTSSGSPPGL AAVPVESAME PWGEWNAWPR PKESAPLEGR APSKSSSLLR
MSAETPPRQD DDAGGTLNTS ASQSPRQGPQ GEATRSPQEA GLQTEPLGAA SQAQEGSDAA
SRKALRRERR KMIEKDILHK VTWDGRNPAC PDASRGKEKA CDAVEVPSEG PPGCLPVLSL
QELEEWDLDQ VLLSLTGREE DRGDGAPGAA WWAAGRLQGQ DHTEPSTQDR LMERLSLLCA
RQSRETCRAQ PGYGTARERV GSSSSSGHLG RRPLGLSCPP ARVLSVRRLR PLEIRPGPAL
G