ID   DAAF8_MACFA             Reviewed;         535 AA.
AC   Q95JW1;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Dynein axonemal assembly factor 8 {ECO:0000305};
DE   AltName: Full=Dynein axonemal-associated protein 1 {ECO:0000305};
DE   AltName: Full=Uncharacterized protein C16orf71 homolog;
GN   Name=DNAAF8; Synonyms=DAAP1 {ECO:0000250|UniProtKB:Q8IYS4};
GN   ORFNames=QtsA-10439;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=12498619; DOI=10.1186/1471-2164-3-36;
RA   Osada N., Hida M., Kusuda J., Tanuma R., Hirata M., Suto Y., Hirai M.,
RA   Terao K., Sugano S., Hashimoto K.;
RT   "Cynomolgus monkey testicular cDNAs for discovery of novel human genes in
RT   the human genome sequence.";
RL   BMC Genomics 3:36-36(2002).
CC   -!- FUNCTION: In cyliated cells, dynein axonemal particle-specific protein
CC       required for deployment of ODA to the axoneme. Interacts with outer
CC       dynein arm (ODA) subunits. {ECO:0000250|UniProtKB:A0A1L8EYB2}.
CC   -!- SUBCELLULAR LOCATION: Dynein axonemal particle
CC       {ECO:0000250|UniProtKB:Q8IYS4}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB070067; BAB63012.1; -; mRNA.
DR   RefSeq; NP_001270887.1; NM_001283958.1.
DR   AlphaFoldDB; Q95JW1; -.
DR   GeneID; 102138483; -.
DR   CTD; 146562; -.
DR   eggNOG; ENOG502SAQ4; Eukaryota.
DR   OrthoDB; 1111863at2759; -.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0120293; C:dynein axonemal particle; ISS:UniProtKB.
DR   GO; GO:0070840; F:dynein complex binding; ISS:UniProtKB.
DR   GO; GO:0036158; P:outer dynein arm assembly; ISS:UniProtKB.
DR   InterPro; IPR031531; DNAAF8.
DR   PANTHER; PTHR35977; PTHR35977; 1.
DR   Pfam; PF15773; DUF4701; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Phosphoprotein; Reference proteome.
FT   CHAIN           1..535
FT                   /note="Dynein axonemal assembly factor 8"
FT                   /id="PRO_0000294346"
FT   REGION          112..215
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          228..267
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          344..380
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          395..444
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          461..535
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        120..135
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..178
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         175
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5XIK6"
FT   MOD_RES         362
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5XIK6"
SQ   SEQUENCE   535 AA;  57143 MW;  D3462DE56D715111 CRC64;
     MASNDEGMAP SLGSPWASQT GPWDAILKAV KDQLPSLDSD SSLSDYGEEE LSIFQRNQTA
     LIPDLSEELA EDPADGDKSR TWAAAAEESL PEVCGTQKSV RLCVCNPALV PAELATEPGN
     RRNTRTKDAS SQEGRDPGRP VETSGEVSAF LGMAEETPRW LGSDLGSLSF NTKGSQGPPW
     DPQAKASLSR HEGDPKAEPA SQESVNRRAL RQERRKMIEK DILQKVTRDA CGPASSDQGG
     VKEAPCHAVE SAARSKMPLA EPPEGPPVLS LQQLEAWDLD YILQSLAGQE DNQGNRGPGT
     VWWAADRRQV QDRTVPSADD RLMEQLALLC TMQSRASACA WKVPADTPQD TEEAGAGSRC
     SSRKPGSEAG PGPQLAQGMR LNTEPPTIFI DLRQTVPPDH LSPARSRGSS HSSSDSEEEE
     EEVEMAALGD AEGASPSSLG LRSCTGKSQL LQQLRAFRKG IAQPKLPANK GPGGERAQAP
     EDTAASGTVR KQHMKLCAKG QSAQARLPRG RPRALGDAPE PGAAREALMP PLDQL