ID   DAAF9_MOUSE             Reviewed;        1179 AA.
AC   Q7TT23; Q3UPD4;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 2.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Dynein axonemal assembly factor 9 {ECO:0000305};
DE            Short=DNAAF9 {ECO:0000305};
GN   Name=Dnaaf9 {ECO:0000312|MGI:MGI:1923029};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Spleen;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brown adipose tissue, Liver, and Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- FUNCTION: May act as an effector for ARL3. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with ARL3. {ECO:0000250}.
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DR   EMBL; AK143611; BAE25462.1; -; mRNA.
DR   EMBL; BC052447; AAH52447.2; -; mRNA.
DR   CCDS; CCDS16750.1; -.
DR   RefSeq; NP_083708.1; NM_029432.2.
DR   AlphaFoldDB; Q7TT23; -.
DR   STRING; 10090.ENSMUSP00000046992; -.
DR   iPTMnet; Q7TT23; -.
DR   PhosphoSitePlus; Q7TT23; -.
DR   MaxQB; Q7TT23; -.
DR   PaxDb; Q7TT23; -.
DR   PRIDE; Q7TT23; -.
DR   Antibodypedia; 23528; 77 antibodies from 16 providers.
DR   DNASU; 228602; -.
DR   Ensembl; ENSMUST00000044766; ENSMUSP00000046992; ENSMUSG00000027309.
DR   GeneID; 228602; -.
DR   KEGG; mmu:228602; -.
DR   UCSC; uc008mjw.1; mouse.
DR   CTD; 25943; -.
DR   MGI; MGI:1923029; Dnaaf9.
DR   VEuPathDB; HostDB:ENSMUSG00000027309; -.
DR   eggNOG; ENOG502QUJP; Eukaryota.
DR   GeneTree; ENSGT00390000003692; -.
DR   HOGENOM; CLU_008324_0_0_1; -.
DR   InParanoid; Q7TT23; -.
DR   OMA; KMTFHIH; -.
DR   OrthoDB; 226711at2759; -.
DR   PhylomeDB; Q7TT23; -.
DR   TreeFam; TF329802; -.
DR   BioGRID-ORCS; 228602; 2 hits in 74 CRISPR screens.
DR   PRO; PR:Q7TT23; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   RNAct; Q7TT23; protein.
DR   Bgee; ENSMUSG00000027309; Expressed in rostral migratory stream and 231 other tissues.
DR   ExpressionAtlas; Q7TT23; baseline and differential.
DR   Genevisible; Q7TT23; MM.
DR   InterPro; IPR040342; C20orf194-like.
DR   PANTHER; PTHR33664; PTHR33664; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..1179
FT                   /note="Dynein axonemal assembly factor 9"
FT                   /id="PRO_0000236043"
FT   CONFLICT        175
FT                   /note="D -> E (in Ref. 1; BAE25462)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        307
FT                   /note="F -> L (in Ref. 1; BAE25462)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1179 AA;  132207 MW;  9264C5F608710D1F CRC64;
     MDSFDPQQLG LSPARFAGTF GSGAASVSCS RLRQVQSVLT QSSKSQPDGI LCILGIDSRY
     NEGCRELANY LLFGLYSQNA TDFEKTGFSE EILDDVILLI KSDSVHLYCN PVNYRYLLPY
     VAHWRNLHFH CMTENEYEDE EAAEEFKISS FVDMVRDCSR IGIPYSSQGH LQIFDMFVVE
     KWPIVQAFAL EGIGGDGFFT MKYELQDVSL SLWNVYSRMD PASLENMLSE DLAVFEHQWT
     SFFANFDTEI PFLLELSESQ AGEPFRSYFG HGMLSSHITE NSPHRQPFVL FGNHSTRDNL
     SAGSFNFPSE GHLVRNTGPA GSFAKHMVAQ CVSPKGPLAC SRTYFFGATH VPYLGDNEKL
     PRTTEQIRLL SQIYAAVIEA VLAGIACYAK TCSLAKAKEV AEHTLESGLV FTELVPFKAD
     LRSKVTFHIH AVNNQGRIVP LNNEDSLSFV KTARMTVYDI PDLLGGGGGG CLGSVVFSES
     FLTSRILVKE KDGTITPETS YIILTAAIPR FCSWLVEDSE IKLSEKTLQA TKGDDCCLGT
     LLTGGKGAYL YSNSPQSGPE EGSAYFFSGG LLFSHRHHGS IVIAKEHVDA FSFYDGDSTS
     VVAALLIHFR SSILPHLPVH FHGSSNFLML ALFPKSKIYQ AFYSEVFSPW QQQDNSGLSL
     KVIQEDGLSA EQKRLHSNAQ KLFSALSPPA QDWSSPKLLS GKLPELDRFL QHFAIGSIGQ
     EPVMRAHLVG LLQQPEMSPA HEVESDKVVI SIVTGLPGCH ASKLCAFLIT LHKEYGRWMV
     YRQIMDSSEC FHAAHFQKYL SSALEAQQNR SARQSAYIRK KTRLLVVLQG YTDVIDVVQA
     LQTHPDPNVR SYFTIGAVTV CVEPLSCYME HRFLFPKCLD QCSQGVVSNV VFTSHTAEQK
     HPLLVQLQTL IRASNPTAAF ILAENGIVTR NEDIELILSE NSFSSPQMLR SRYLLFPGWY
     EGKFDAGSVF PLMVQICVWF DCPLEKTRFV SRCRAIQSSI KPSPFSGNIY HILGKVKFSD
     SEKTMEVCHN TLTNSLTIVP VLEGPTPPPN SRSSPQDNGQ PECYLVFIGC SLKEDSLKDW
     LRQSAKQRPQ RKALKTRGML TQQEIKNIHV KRHLDPLPAG YFYNGTQFVN FFGDKTDFHP
     LMDQFMNDYV EEANREIERY NRELEQQEYR DLFEQKPKP