ID   DABA1_HALNC             Reviewed;        1046 AA.
AC   D0KZ77;
DT   29-SEP-2021, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2009, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Probable inorganic carbon transporter subunit DabA1 {ECO:0000255|HAMAP-Rule:MF_01871, ECO:0000303|PubMed:31406332};
GN   Name=dabA1 {ECO:0000255|HAMAP-Rule:MF_01871, ECO:0000303|PubMed:31406332};
GN   OrderedLocusNames=Hneap_0907 {ECO:0000312|EMBL:ACX95750.1};
OS   Halothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus
OS   neapolitanus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC   Halothiobacillaceae; Halothiobacillus.
OX   NCBI_TaxID=555778;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23641 / c2;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Davenport K., Brettin T., Detter J.C., Han C.,
RA   Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Kerfeld C., Cannon G., Heinhort S.;
RT   "Complete sequence of Halothiobacillus neapolitanus c2.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=ATCC 23641 / c2;
RX   PubMed=31406332; DOI=10.1038/s41564-019-0520-8;
RA   Desmarais J.J., Flamholz A.I., Blikstad C., Dugan E.J., Laughlin T.G.,
RA   Oltrogge L.M., Chen A.W., Wetmore K., Diamond S., Wang J.Y., Savage D.F.;
RT   "DABs are inorganic carbon pumps found throughout prokaryotic phyla.";
RL   Nat. Microbiol. 4:2204-2215(2019).
CC   -!- FUNCTION: Part of an energy-coupled inorganic carbon pump.
CC       {ECO:0000255|HAMAP-Rule:MF_01871, ECO:0000305|PubMed:31406332}.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01871};
CC   -!- SUBUNIT: Forms a complex with DabB1. {ECO:0000255|HAMAP-Rule:MF_01871}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01871}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01871}.
CC   -!- DISRUPTION PHENOTYPE: Required for growth in ambient air.
CC       {ECO:0000269|PubMed:31406332}.
CC   -!- SIMILARITY: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA
CC       family. {ECO:0000255|HAMAP-Rule:MF_01871}.
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DR   EMBL; CP001801; ACX95750.1; -; Genomic_DNA.
DR   STRING; 555778.Hneap_0907; -.
DR   EnsemblBacteria; ACX95750; ACX95750; Hneap_0907.
DR   KEGG; hna:Hneap_0907; -.
DR   eggNOG; COG3002; Bacteria.
DR   HOGENOM; CLU_009885_0_0_6; -.
DR   OMA; FWPMRTF; -.
DR   OrthoDB; 179501at2; -.
DR   Proteomes; UP000009102; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01871; DabA; 1.
DR   InterPro; IPR018752; DabA.
DR   PANTHER; PTHR38344; PTHR38344; 1.
DR   Pfam; PF10070; MpsB; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Metal-binding;
KW   Reference proteome; Transport; Zinc.
FT   CHAIN           1..1046
FT                   /note="Probable inorganic carbon transporter subunit DabA1"
FT                   /id="PRO_0000453153"
FT   BINDING         462
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01871"
FT   BINDING         464
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01871"
FT   BINDING         721
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01871"
FT   BINDING         736
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01871"
SQ   SEQUENCE   1046 AA;  118414 MW;  9ED50E1119EA428E CRC64;
     MSKLPLGKRL KIRSMVHMAA EPIPNFWPMR TFIHHNPLHG LEHLPFEQAV RQGEKLFHAR
     GFLPREDYQR YHKEGRVDQN SIKRDIADFI SKQETLNGLD LASLLSDLMC SVKNKVTRTR
     ALADHDDVFQ ALHGKQLENA EALDLKALTQ RLCAQFAPER PLYEAIDLLF GTQMGTTLDE
     LVIKSCLDFF DEGQSTIQMP GRHQGLFAAW TALAKRNLRL FLRGMHIKQI LDQDDTPEGI
     IAYILDELGI EEAHWDGLIT RELTRLHGWA GFIRWRSSSK HYYWAEQYPG DLIDFLAIRL
     VLGLALIREH SRQKRTPMTV KVLQEYIEGH TAECYLRQAY YGGCILPAFA HDVDDALSHK
     KPQRINNILP GYLRQQRQFE ATRQADALRD LASKAGQTDA LMALNAPQIK QLMTLIEAFE
     NEEGMIWLRA MESVYRREII NQIQLYAPHK KEKRPFAQAL FCIDVRSEPI RRNLETVGEY
     QTYGIAGFFG VPVSYIGLGK GSEVNLCPVV ITPKNLVLEV PVGATSIETD FYSSADHVLH
     EMKSSILSPY FTVEAAGLLF GFDMIGKTIA PRRYTQIRNH IEPKAQATRL LVDKLTREQA
     DSIVRSLQRA MIVRAIHQEF GIEREAVTDA MIRELREAAM DNYHEQTEFA RRFALSPTAE
     TQFIAGLKKD YKINRSFVSM QMERLARIGF SLDEQVFYVD KALTSIGLTE NFSRFVLLAG
     HGSTSDNNPY ESALDCGACG GSHGLVSARV LAHMANKPEV RRRLAKQGIQ IPEDTWFVSV
     MHNTTTDQLS LQDLDLLPNS HLVYLERLRN GLRAATRLSA AERLPALLDH PSPNIDTLSA
     QKQIERNASD WTQVRPEWGL ARNASVVAGG RHLTEGANLS GRTFLQSYDY RLDPKGRHLE
     NILSNPLIIG QWINLEHYFS AVDNEHFGSG SKAYHNVVGR FGVVTGNLSD LRTGLPAQSV
     LKDGRPYHEP IRLLAIIEAP AAFTLEVAGR LPKVMSLITN GWITVVVVDP ETGDRLFYDR
     GEWYNLNNDP QYTPSVKPLL EEELSA