位置:首页 > 蛋白库 > DABA_BACAN
DABA_BACAN
ID   DABA_BACAN              Reviewed;         874 AA.
AC   Q81NL0; Q6HWS3; Q6KQW6;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Probable inorganic carbon transporter subunit DabA {ECO:0000255|HAMAP-Rule:MF_01871, ECO:0000303|PubMed:31406332};
GN   Name=dabA {ECO:0000255|HAMAP-Rule:MF_01871, ECO:0000303|PubMed:31406332};
GN   OrderedLocusNames=BA_3182, GBAA_3182, BAS2958;
OS   Bacillus anthracis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames / isolate Porton;
RX   PubMed=12721629; DOI=10.1038/nature01586;
RA   Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T.,
RA   Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R.,
RA   Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M.,
RA   Kolonay J.F., Beanan M.J., Dodson R.J., Brinkac L.M., Gwinn M.L.,
RA   DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C.,
RA   Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y.,
RA   Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M.,
RA   Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E.,
RA   White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M.,
RA   Hanna P.C., Kolstoe A.-B., Fraser C.M.;
RT   "The genome sequence of Bacillus anthracis Ames and comparison to closely
RT   related bacteria.";
RL   Nature 423:81-86(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sterne;
RA   Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K.,
RA   Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R.,
RA   Richardson P., Rubin E., Tice H.;
RT   "Complete genome sequence of Bacillus anthracis Sterne.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames ancestor;
RX   PubMed=18952800; DOI=10.1128/jb.01347-08;
RA   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA   Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT   "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL   J. Bacteriol. 191:445-446(2009).
RN   [4]
RP   FUNCTION, AND EXPRESSION IN ECOLI.
RC   STRAIN=Sterne;
RX   PubMed=31406332; DOI=10.1038/s41564-019-0520-8;
RA   Desmarais J.J., Flamholz A.I., Blikstad C., Dugan E.J., Laughlin T.G.,
RA   Oltrogge L.M., Chen A.W., Wetmore K., Diamond S., Wang J.Y., Savage D.F.;
RT   "DABs are inorganic carbon pumps found throughout prokaryotic phyla.";
RL   Nat. Microbiol. 4:2204-2215(2019).
CC   -!- FUNCTION: Part of an energy-coupled inorganic carbon pump.
CC       {ECO:0000255|HAMAP-Rule:MF_01871}.
CC   -!- FUNCTION: Expression of both dabA and dabB (DA2) restores growth in
CC       ambient air to E.coli deleted of its carbonic anhydrase genes (called
CC       CAfree, deletion of 'can' and 'cynT'). {ECO:0000269|PubMed:31406332}.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01871};
CC   -!- SUBUNIT: Forms a complex with DabB. {ECO:0000255|HAMAP-Rule:MF_01871}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01871};
CC       Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01871}.
CC   -!- SIMILARITY: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA
CC       family. {ECO:0000255|HAMAP-Rule:MF_01871}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE016879; AAP26978.1; -; Genomic_DNA.
DR   EMBL; AE017334; AAT32298.1; -; Genomic_DNA.
DR   EMBL; AE017225; AAT55266.1; -; Genomic_DNA.
DR   RefSeq; NP_845492.1; NC_003997.3.
DR   RefSeq; WP_000026985.1; NZ_WXXJ01000008.1.
DR   RefSeq; YP_029215.1; NC_005945.1.
DR   AlphaFoldDB; Q81NL0; -.
DR   SMR; Q81NL0; -.
DR   STRING; 260799.BAS2958; -.
DR   DNASU; 1086884; -.
DR   EnsemblBacteria; AAP26978; AAP26978; BA_3182.
DR   EnsemblBacteria; AAT32298; AAT32298; GBAA_3182.
DR   GeneID; 45022968; -.
DR   KEGG; ban:BA_3182; -.
DR   KEGG; bar:GBAA_3182; -.
DR   KEGG; bat:BAS2958; -.
DR   PATRIC; fig|198094.11.peg.3167; -.
DR   eggNOG; COG3002; Bacteria.
DR   HOGENOM; CLU_009885_0_0_9; -.
DR   OMA; DCDLEGR; -.
DR   Proteomes; UP000000427; Chromosome.
DR   Proteomes; UP000000594; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01871; DabA; 1.
DR   InterPro; IPR018752; DabA.
DR   PANTHER; PTHR38344; PTHR38344; 1.
DR   Pfam; PF10070; MpsB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Metal-binding; Reference proteome; Transport;
KW   Zinc.
FT   CHAIN           1..874
FT                   /note="Probable inorganic carbon transporter subunit DabA"
FT                   /id="PRO_0000387234"
FT   BINDING         398
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01871"
FT   BINDING         400
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01871"
FT   BINDING         580
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01871"
FT   BINDING         595
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01871"
SQ   SEQUENCE   874 AA;  99265 MW;  3534B9241049326B CRC64;
     MSIPSILRKE TLKKKDKNID LQENNINDLV VSASRVIAPL WPISTFAAHH PWMGLEKQSF
     EQVANWLKEA RNVDIYPSAS MIHSAKAKGE IEESFLQIAL SRWLDSQSFH MPRETAERFC
     QEALKLERLP SSLLSSPELN KLAEEINYVN TGSMKDSSMQ PISSLIENQN GDNLSDILNY
     HIIKWCKLYL DDAGASWAMP NREKGFYRAW QHLITFDPAL SKTERKVLKD WPEDALIALT
     KALSELGISE SNMQAYLEGH LLSLPGWAGM IRWRSQQSIE EQELLIEYLA VRLSMELAIV
     KPYLPLKNQK VEKKVSIVPL IASWIYWGDI SIEKWLQMSA TEQSELLAFA YRFDENTRKK
     LWLEAWEQTH AEQLREKIAS KQRATHDKKR VVAQLAFCID VRSEPFRRHL EKLGPFETFG
     IAGFFGLPIA TTELGSNDSH PSLPVILKPK HQIKELTDEN ECKSYEQRKM VGSSVRYTFK
     TMKQNVLTSM LLPEVSGPLL GLQMVTRSFV PRRVGGFIRN LRKNMLQKPD TTFSLNHVHD
     TNCEIPIGFT KEEKVNYVRQ TLKMVGLTEG FAPLVVMCGH SSQSTNNPYA AALECGACGG
     AAGGFNARVF ATLCNLPEVR EALSAEGIKI PDDTIFAAAE HKTTVDELEW IYVPELSETA
     QEAFDCIEAI MPNVSQHANR ERLMQLPHFK TKIKNPSKEA HRFAEDWSEI RPEWGLARNA
     SFIIGQRELT QECDLEGRAF LHNYDWKQDE SGDILANIIA GPGTVAQWIN LQYYASTVAP
     HYYGSGNKAT QTVTAGLGVM QGNASDLLPG LPWQSVMQSD RETYHSPLRL LIVIQAPTKY
     IERLLNNNFT FREKVQNGWV RLASVDPEGR WKNW
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024